Literature summary for 1.1.1.284 extracted from

Oka, T.; Komachi, Y.; Ohshima, K.; Kawano, Y.; Fukuda, K.; Nagahama, K.; Ekino, K.; Nomura, Y.
Isolation, sequencing, and heterologous expression of the Paecilomyces variotii gene encoding S-hydroxymethylglutathione dehydrogenase (fldA) (2015), Appl. Microbiol. Biotechnol., 99, 1755-1763.

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Application

Application	Comment	Organism
degradation	a Saccharomyces cerevisiae mutant lacking the gene for S-hydroxymethylglutathione dehydrogenase and expressing FldA is able to degrade 4 mM formaldehyde within 30 h	Paecilomyces variotii

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
41000	-	-	Paecilomyces variotii

Organism

Organism	UniProt	Comment	Textmining
Paecilomyces variotii	U6C832	-	-
Paecilomyces variotii NBRC 109023	U6C832	-	-

Subunits

Subunits	Comment	Organism
?	x * 41000, SDS-PAGE, recombinant protein with His-tag	Paecilomyces variotii

Synonyms

Synonyms	Comment	Organism
FldA	-	Paecilomyces variotii

General Information

General Information	Comment	Organism
physiological function	the FldA gene is able to functionally complement a Saccharomyces cerevisiae strain lacking the gene for S-hydroxymethylglutathione dehydrogenase. The expression renders the Sacchamormyces cerevisiae mutant strain tolerant to exogenous formaldehyde. Although the parent strain is unable to degrade even low concentrations of formaldehyde, the recombinant strain is able to degrade 4 mM formaldehyde within 30 h	Paecilomyces variotii

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Release 2023.1 (January 2023)