BRENDA - Enzyme Database show
show all sequences of 1.1.1.275

Biosynthesis of the monoterpenes limonene and carvone in the fruit of caraway. I. Demonstration of enzyme activities and their changes with development

Bouwmeester, H.J.; Gershenzon, J.; Konings, M.C.J.M.; Croteau, R.; Plant Physiol. 117, 901-912 (1998)

Data extracted from this reference:

Localization
Localization
Commentary
Organism
GeneOntology No.
Textmining
cytosol
-
Carum carvi
5829
-
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
(+)-trans-carveol + NAD+
Carum carvi
enzyme catalyses the final step of (+)-carvone biosynthesis, which is developmentally regulated, key enzyme of the pathway is limonene-6-hydroxylase
(+)-carvone + NADH
-
Carum carvi
?
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Carum carvi
-
var. Karzo
-
Source Tissue
Source Tissue
Commentary
Organism
Textmining
fruit
-
Carum carvi
-
additional information
developmental regulation, overview
Carum carvi
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
(+)-trans-carveol + NAD+
best substrate
639021
Carum carvi
(+)-carvone + NADH
-
639021
Carum carvi
?
(+)-trans-carveol + NAD+
stereospecificity
639021
Carum carvi
(+)-carvone + NADH
-
639021
Carum carvi
?
(+)-trans-carveol + NAD+
enzyme catalyses the final step of (+)-carvone biosynthesis, which is developmentally regulated, key enzyme of the pathway is limonene-6-hydroxylase
639021
Carum carvi
(+)-carvone + NADH
-
639021
Carum carvi
?
(-)-cis-carveol + NAD+
65% activity compared to (+)/(-)-trans-carveol
639021
Carum carvi
(-)-carvone + NADH
-
639021
Carum carvi
?
(-)-trans-carveol + NAD+
5% activity compared to (+)/(-)-trans-carveol
639021
Carum carvi
?
-
-
-
?
(-)-trans-carveol + NAD+
product identification not possible, below detection limit of GC-MS
639021
Carum carvi
?
-
-
-
?
(-)/(+)-cis-carveol + NAD+
-
639021
Carum carvi
(-)-carvone + NADH
-
639021
Carum carvi
?
Temperature Optimum [°C]
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
30
-
assay at
Carum carvi
pH Optimum
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
10
-
about
Carum carvi
Cofactor
Cofactor
Commentary
Organism
Structure
NAD+
absolutely dependent on, NADP+ cannot substitute for NAD+ and cannot act synergistically
Carum carvi
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
NAD+
absolutely dependent on, NADP+ cannot substitute for NAD+ and cannot act synergistically
Carum carvi
Localization (protein specific)
Localization
Commentary
Organism
GeneOntology No.
Textmining
cytosol
-
Carum carvi
5829
-
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
(+)-trans-carveol + NAD+
Carum carvi
enzyme catalyses the final step of (+)-carvone biosynthesis, which is developmentally regulated, key enzyme of the pathway is limonene-6-hydroxylase
(+)-carvone + NADH
-
Carum carvi
?
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
fruit
-
Carum carvi
-
additional information
developmental regulation, overview
Carum carvi
-
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
(+)-trans-carveol + NAD+
best substrate
639021
Carum carvi
(+)-carvone + NADH
-
639021
Carum carvi
?
(+)-trans-carveol + NAD+
stereospecificity
639021
Carum carvi
(+)-carvone + NADH
-
639021
Carum carvi
?
(+)-trans-carveol + NAD+
enzyme catalyses the final step of (+)-carvone biosynthesis, which is developmentally regulated, key enzyme of the pathway is limonene-6-hydroxylase
639021
Carum carvi
(+)-carvone + NADH
-
639021
Carum carvi
?
(-)-cis-carveol + NAD+
65% activity compared to (+)/(-)-trans-carveol
639021
Carum carvi
(-)-carvone + NADH
-
639021
Carum carvi
?
(-)-trans-carveol + NAD+
5% activity compared to (+)/(-)-trans-carveol
639021
Carum carvi
?
-
-
-
?
(-)-trans-carveol + NAD+
product identification not possible, below detection limit of GC-MS
639021
Carum carvi
?
-
-
-
?
(-)/(+)-cis-carveol + NAD+
-
639021
Carum carvi
(-)-carvone + NADH
-
639021
Carum carvi
?
Temperature Optimum [°C] (protein specific)
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
30
-
assay at
Carum carvi
pH Optimum (protein specific)
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
10
-
about
Carum carvi
Other publictions for EC 1.1.1.275
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
741432
Haft
Mycofactocin-associated mycoba ...
Mycobacterium avium 104, Mycobacterium avium, Mycobacterium avium subsp. paratuberculosis, Mycobacterium avium subsp. paratuberculosis ATCC BAA-968
Sci. Rep.
7
41074
2017
-
-
-
2
-
-
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-
-
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-
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12
-
-
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-
-
-
-
-
-
-
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-
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-
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6
-
-
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-
-
-
-
-
-
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-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
639355
Duetz
Biotransformation of D-limonen ...
Rhodococcus opacus, Rhodococcus opacus PWD4 / DSM 44313
Appl. Environ. Microbiol.
67
2829-2832
2001
-
1
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-
-
-
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-
-
-
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2
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2
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1
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1
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1
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-
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-
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2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
639021
Bouwmeester
Biosynthesis of the monoterpen ...
Carum carvi
Plant Physiol.
117
901-912
1998
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-
-
-
-
-
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1
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1
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1
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-
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2
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7
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1
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1
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1
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1
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1
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1
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2
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7
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1
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1
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