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Literature summary for 1.1.1.252 extracted from
- Post-aromatic deoxygenation in polyketide biosynthesis: reduction of aromatic rings in the biosynthesis of fungal melanin and anthraquinone (1993), Chem. Pharm. Bull., 41, 2015-2021.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 1,3,6,8-Tetrahydroxynaphthalene + NADPH | Phialocephala lagerbergii | the enzyme is involved in the post-aromatic deoxygenation process of fungal melanin and pigments | Scytalone + NADP+ | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Phialocephala lagerbergii | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| partial | Phialocephala lagerbergii |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
- |
Phialocephala lagerbergii |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 1,3,6,8-Tetrahydroxynaphthalene + NADPH | - |
Phialocephala lagerbergii | Scytalone + NADP+ | - |
? | |
| 1,3,6,8-Tetrahydroxynaphthalene + NADPH | the enzyme is involved in the post-aromatic deoxygenation process of fungal melanin and pigments | Phialocephala lagerbergii | Scytalone + NADP+ | - |
? | |
| 1,3,8-trihydroxynaphthalene + NADPH + H+ | - |
Phialocephala lagerbergii | vermelone + NADP+ | - |
? | |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NADPH | - |
Phialocephala lagerbergii | |
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Release 2023.1 (January 2023)
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