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Literature summary for 1.1.1.252 extracted from
- Polyhydroxynaphthalene reductase involved in melanin biosynthesis in Magnaporthe grisea. Purification, cDNA cloning and sequencing (1994), Eur. J. Biochem., 219, 985-992.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
- |
Pyricularia grisea |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 29900 | - |
4 * 29900, calculation from nucleotide sequence | Pyricularia grisea |
| 30000 | - |
4 * 30000, SDS-PAGE | Pyricularia grisea |
| 120400 | - |
gel filtration | Pyricularia grisea |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 1,3,6,8-Tetrahydroxynaphthalene + NADPH | Pyricularia grisea | the enzyme is involved in the biosynthesis of melanin | Scytalone + NADP+ | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Pyricularia grisea | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Pyricularia grisea |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 18.4 | - |
- |
Pyricularia grisea |
Storage Stability
| Storage Stability | Organism |
|---|---|
| -20°C, with glycerol, stable over several months | Pyricularia grisea |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 1,3,6,8-Tetrahydroxynaphthalene + NADPH | - |
Pyricularia grisea | Scytalone + NADP+ | - |
? | |
| 1,3,6,8-Tetrahydroxynaphthalene + NADPH | the enzyme is involved in the biosynthesis of melanin | Pyricularia grisea | Scytalone + NADP+ | - |
? | |
| 1,3,8-trihydroxynaphthalene + NADPH + H+ | - |
Pyricularia grisea | vermelone + NADP+ | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| tetramer | 4 * 30000, SDS-PAGE | Pyricularia grisea |
| tetramer | 4 * 29900, calculation from nucleotide sequence | Pyricularia grisea |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NADPH | - |
Pyricularia grisea | |
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