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Literature summary for 1.1.1.25 extracted from
- Aromatic biosynthesis in higher plants I. Preparation and properties of dehydroshikimic reductase (1961), Biochem. J., 80, 292-296.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| iodoacetate | slight | Pisum sativum |  |
| p-chloromercuribenzoate | - |
Pisum sativum | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.007 | - |
NADP+ | - |
Pisum sativum | |
| 0.19 | 0.28 | shikimate | - |
Pisum sativum | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| additional information | no metal ion requirement | Pisum sativum |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 57000 | - |
- |
Pisum sativum |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 3-dehydroshikimate + NADPH | Pisum sativum | enzyme of shikimic acid biosynthesis | ? | - |
r | |
| 3-dehydroshikimate + NADPH | Pisum sativum | pathway of biosynthesis of aromatic amino acids | ? | - |
r | |
| shikimate + NADP+ | Pisum sativum | - |
3-dehydroshikimate + NADPH + H+ | - |
r | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Pisum sativum | - |
pea | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Pisum sativum |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| epicotyl | etiolated | Pisum sativum | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 3-dehydroshikimate + NADPH | enzyme of shikimic acid biosynthesis | Pisum sativum | ? | - |
r | |
| 3-dehydroshikimate + NADPH | pathway of biosynthesis of aromatic amino acids | Pisum sativum | ? | - |
r | |
| shikimate + NADP+ | - |
Pisum sativum | 3-dehydroshikimate + NADPH + H+ | - |
r | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 10 | - |
- |
Pisum sativum |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 8.5 | 10.5 | pH 8.5: about 50% of activity maximum, pH 10.5: about 90% of activity maximum | Pisum sativum |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| additional information | no activity with NAD+ | Pisum sativum | |
| NADP+ | - |
Pisum sativum | |
| NADPH | - |
Pisum sativum | |
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Release 2023.1 (January 2023)
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