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show all sequences of 1.1.1.243

Mycofactocin-associated mycobacterial dehydrogenases with non-exchangeable NAD cofactors

Haft, D.H.; Pierce, P.G.; Mayclin, S.J.; Sullivan, A.; Gardberg, A.S.; Abendroth, J.; Begley, D.W.; Phan, I.Q.; Staker, B.L.; Myler, P.J.; Marathias, V.M.; Lorimer, D.D.; Edwards, T.E.; Sci. Rep. 7, 41074 (2017)

Data extracted from this reference:

Crystallization (Commentary)
Crystallization
Organism
to 1.95 A resolution. STD-NMR demonstrates binding of the potential substrate carveol, the potential product carvone, the inhibitor tricyclazol, and external redox partner 2,6-dichloroindophenol. The enzyme appears to contain a non-exchangeable NAD cofactor and may rely on an external redox partner, rather than cofactor exchange, for multiple turnover
Mycolicibacterium thermoresistibile
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Mycolicibacterium thermoresistibile
E1C9L4
-
-
Crystallization (Commentary) (protein specific)
Crystallization
Organism
to 1.95 A resolution. STD-NMR demonstrates binding of the potential substrate carveol, the potential product carvone, the inhibitor tricyclazol, and external redox partner 2,6-dichloroindophenol. The enzyme appears to contain a non-exchangeable NAD cofactor and may rely on an external redox partner, rather than cofactor exchange, for multiple turnover
Mycolicibacterium thermoresistibile
Other publictions for EC 1.1.1.243
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
741432
Haft
Mycofactocin-associated mycoba ...
Mycolicibacterium thermoresistibile
Sci. Rep.
7
41074
2017
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670589
Ringer
Monoterpene metabolism. Clonin ...
Mentha spicata
Plant Physiol.
137
863-872
2005
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1
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1
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1
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656954
Carter
Monoterpene biosynthesis pathw ...
Mentha spicata
Phytochemistry
64
425-433
2003
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1
1
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1
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3
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286371
Tecelao
-
Development of a reaction syst ...
Rhodococcus erythropolis
J. Mol. Catal. , B Enzym.
11
719-724
2001
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656560
Tecelao
-
Development of a reaction syst ...
Rhodococcus erythropolis, Rhodococcus erythropolis DCL14
J. Mol. Catal. B
11
719-724
2001
2
2
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2
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7
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1
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4
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1
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2
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1
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1
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4
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1
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1
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286370
van der Werf
Metabolism of carveol and dihy ...
Rhodococcus erythropolis
Microbiology
146
1129-1141
2000
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9
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286369
van der Werft
Stereoselective carveol dehydr ...
Rhodococcus erythropolis, Rhodococcus erythropolis DCL14
J. Biol. Chem.
274
26296-26304
1999
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4
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2
2
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10
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1
1
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1
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24
1
1
1
1
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1
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4
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2
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1
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24
1
1
1
1
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1
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286368
Gershenzon
Biochemical and histochemical ...
Mentha spicata
Plant Physiol.
89
1351-1357
1989
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