Literature summary for 1.1.1.236 extracted from

Yamashita, A.; Endo, M.; Higashi, T.; Nakatsu, T.; Yamada, Y.; Oda, J.; Kato, H.
Capturing enzyme structure prior to reaction initiation: tropinone reductase-II-substrate complexes (2003), Biochemistry, 42, 5566-5573.

Search for more literature for 1.1.1.236

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
0.0171	-	NADPH	pH 7.5, 15°C	Datura stramonium
0.0949	-	tropinone	pH 7.5, 15°C	Datura stramonium

Organism

Organism	UniProt	Comment	Textmining
Datura stramonium	P50163	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
tropinone + NADPH + H+	one of the substrates, tropinone, is rotated relative to the en product so as to make the spatial organization in the active site favorable for the reaction to proceed	Datura stramonium	pseudotropine + NADP+	-	?

Synonyms

Synonyms	Comment	Organism
TR-II	-	Datura stramonium
tropinone reductase-II	-	Datura stramonium

Turnover Number [1/s]

Turnover Number Minimum [1/s]	Turnover Number Maximum [1/s]	Substrate	Comment	Organism	Structure
71.4	-	NADPH	pH 7.5, 15°C	Datura stramonium
71.4	-	tropinone	pH 7.5, 15°C	Datura stramonium

Cofactor

Cofactor	Comment	Organism	Structure
NADPH	-	Datura stramonium

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Release 2023.1 (January 2023)