Protein Variants | Comment | Organism |
---|---|---|
additional information | comparison of sequence homologies with bacterial enzymes | Bos taurus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
additional information | no metal ion requirement | Bos taurus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
52000 | - |
6 * 52000, gel filtration | Bos taurus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
UDPglucose + NAD+ + H2O | Bos taurus | - |
UDPglucuronate + NADH | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Bos taurus |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
UDP-alpha-D-glucose + 2 NAD+ + H2O = UDP-alpha-D-glucuronate + 2 NADH + 2 H+ | reaction mechanism, C275 provides SH-group in the catalytic centre | Bos taurus | |
UDP-alpha-D-glucose + 2 NAD+ + H2O = UDP-alpha-D-glucuronate + 2 NADH + 2 H+ | also shows aldehyde dehydrogenase activity | Bos taurus | |
UDP-alpha-D-glucose + 2 NAD+ + H2O = UDP-alpha-D-glucuronate + 2 NADH + 2 H+ | also shows alcohol dehydrogenase activity | Bos taurus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Bos taurus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
UDP-glucose + 2 NAD+ + H2O | - |
Bos taurus | UDP-glucuronate + 2 NADH + 2 H+ | - |
? | |
UDPglucose + NAD+ + H2O | - |
Bos taurus | UDPglucuronate + NADH | - |
? |
Subunits | Comment | Organism |
---|---|---|
hexamer | 6 * 52000, gel filtration | Bos taurus |