Literature summary for 1.1.1.205 extracted from

Trapero, A.; Pacitto, A.; Chan, D.S.; Abell, C.; Blundell, T.L.; Ascher, D.B.; Coyne, A.G.
Covalent inactivation of Mycobacterium thermoresistibile inosine-5'-monophosphate dehydrogenase (IMPDH) (2020), Bioorg. Med. Chem. Lett., 30, 126792 .

Search for more literature for 1.1.1.205

Inhibitors

Inhibitors	Comment	Organism	Structure
(2Z)-2fluorovinyl-IMP	-	Mycolicibacterium thermoresistibile
2-chloromethyl-IMP	-	Mycolicibacterium thermoresistibile
2-fluoromehtyl-IMP	-	Mycolicibacterium thermoresistibile
2-vinyl-IMP	-	Mycolicibacterium thermoresistibile
6-chloro-IMP	-	Mycolicibacterium thermoresistibile
EICARMP	-	Mycolicibacterium thermoresistibile

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
IMP + NAD+ + H2O	Mycolicibacterium thermoresistibile	-	XMP + NADH + H+	-	?
IMP + NAD+ + H2O	Mycolicibacterium thermoresistibile ATCC 19527	-	XMP + NADH + H+	-	?

Organism

Organism	UniProt	Comment	Textmining
Mycolicibacterium thermoresistibile	G7CNL4	-	-
Mycolicibacterium thermoresistibile ATCC 19527	G7CNL4	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
IMP + NAD+ + H2O	-	Mycolicibacterium thermoresistibile	XMP + NADH + H+	-	?
IMP + NAD+ + H2O	-	Mycolicibacterium thermoresistibile ATCC 19527	XMP + NADH + H+	-	?

Synonyms

Synonyms	Comment	Organism
IMPDH	-	Mycolicibacterium thermoresistibile
inosine-5'-monophosphate dehydrogenase	-	Mycolicibacterium thermoresistibile

Cofactor

Cofactor	Comment	Organism	Structure
NAD+	-	Mycolicibacterium thermoresistibile

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Release 2023.1 (January 2023)