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Literature summary for 1.1.1.203 extracted from

  • Xu, Y.; Zhu, X.; Chen, Y.; Gong, Y.; Liu, L.
    Expression profiling of genes involved in ascorbate biosynthesis and recycling during fleshy root development in radish (2013), Plant Physiol. Biochem., 70, 269-277 .
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
D-galacturonate + NADPH + H+ Raphanus sativus
-
L-galactonate + NADP+
-
r

Organism

Organism UniProt Comment Textmining
Raphanus sativus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
root skin and flesh. In the skin, the expression of L-galacturonate acid dehydrogenase is correlated with ascorbate levels Raphanus sativus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
D-galacturonate + NADP+
-
Raphanus sativus L-galactono-1,4-lactone + NADPH + H+
-
r
D-galacturonate + NADPH + H+
-
Raphanus sativus L-galactonate + NADP+
-
r

Synonyms

Synonyms Comment Organism
galacturonate acid reductase
-
Raphanus sativus
GalUR
-
Raphanus sativus

Cofactor

Cofactor Comment Organism Structure
NADP+
-
Raphanus sativus
NADPH
-
Raphanus sativus

General Information

General Information Comment Organism
metabolism the enzyme is proposed to be part of the salvage pathway in ascorbate production as galacturonate acid reductase, GalUR, EC 1.1.1.203, converting D-galacturonate to L-galactono-1,4-lactone, ascorbate biosynthesis and recycling pathways in plants, overview Raphanus sativus
physiological function ascorbate accumulation is affected mainly by biosynthesis rather than recycling in radish root, and the L-galactose pathway may be the major biosynthetic route of ascorbate, and moreover, the salvage pathway may also contribute to ascorbate accumulation. Ascorbate level regulation involves the D-galacturonate reductase and GDP-D-mannose diphosphorylase Raphanus sativus