Application | Comment | Organism |
---|---|---|
synthesis | the enzyme can be used for 1,3-propandiol synthesis for use in resaerch and industrial applications, especially in biodiesel industry, but also as a monomer for polycondensation to manufacture plastics with special properties, i.e., polyesters, polyethers, polyurethanes, and polytrimethylene terephthalate as a monomer for cyclic compounds, and as a polyglycol-type lubricant | Klebsiella pneumoniae |
synthesis | the enzyme can be used for 1,3-propandiol synthesis for use in resaerch and industrial applications, especially in biodiesel industry, but also as a monomer for polycondensation to manufacture plastics with special properties, i.e., polyesters, polyethers, polyurethanes, and polytrimethylene terephthalate as a monomer for cyclic compounds, and as a polyglycol-type lubricant | Pantoea agglomerans |
synthesis | the enzyme can be used for 1,3-propandiol synthesis for use in resaerch and industrial applications, especially in biodiesel industry, but also as a monomer for polycondensation to manufacture plastics with special properties, i.e., polyesters, polyethers, polyurethanes, and polytrimethylene terephthalate as a monomer for cyclic compounds, and as a polyglycol-type lubricant | Clostridium pasteurianum |
synthesis | the enzyme can be used for 1,3-propandiol synthesis for use in resaerch and industrial applications, especially in biodiesel industry, but also as a monomer for polycondensation to manufacture plastics with special properties, i.e., polyesters, polyethers, polyurethanes, and polytrimethylene terephthalate as a monomer for cyclic compounds, and as a polyglycol-type lubricant | Levilactobacillus brevis |
synthesis | the enzyme can be used for 1,3-propandiol synthesis for use in resaerch and industrial applications, especially in biodiesel industry, but also as a monomer for polycondensation to manufacture plastics with special properties, i.e., polyesters, polyethers, polyurethanes, and polytrimethylene terephthalate as a monomer for cyclic compounds, and as a polyglycol-type lubricant | Clostridium butyricum |
synthesis | the enzyme can be used for 1,3-propandiol synthesis for use in resaerch and industrial applications, especially in biodiesel industry, but also as a monomer for polycondensation to manufacture plastics with special properties, i.e., polyesters, polyethers, polyurethanes, and polytrimethylene terephthalate as a monomer for cyclic compounds, and as a polyglycol-type lubricant | Citrobacter freundii |
synthesis | the enzyme can be used for 1,3-propandiol synthesis for use in resaerch and industrial applications, especially in biodiesel industry, but also as a monomer for polycondensation to manufacture plastics with special properties, i.e., polyesters, polyethers, polyurethanes, and polytrimethylene terephthalate as a monomer for cyclic compounds, and as a polyglycol-type lubricant | Lentilactobacillus buchneri |
synthesis | the enzyme can be used for 1,3-propandiol synthesis for use in resaerch and industrial applications, especially in biodiesel industry, but also as a monomer for polycondensation to manufacture plastics with special properties, i.e., polyesters, polyethers, polyurethanes, and polytrimethylene terephthalate as a monomer for cyclic compounds, and as a polyglycol-type lubricant | Clostridium perfringens |
synthesis | the enzyme can be used for 1,3-propandiol synthesis for use in resaerch and industrial applications, especially in biodiesel industry, but also as a monomer for polycondensation to manufacture plastics with special properties, i.e., polyesters, polyethers, polyurethanes, and polytrimethylene terephthalate as a monomer for cyclic compounds, and as a polyglycol-type lubricant | Thermotoga maritima |
synthesis | the enzyme can be used for 1,3-propandiol synthesis for use in resaerch and industrial applications, especially in biodiesel industry, but also as a monomer for polycondensation to manufacture plastics with special properties, i.e., polyesters, polyethers, polyurethanes, and polytrimethylene terephthalate as a monomer for cyclic compounds, and as a polyglycol-type lubricant | Limosilactobacillus reuteri |
Cloned (Comment) | Organism |
---|---|
gene dhaT, part of the dha regulon, genetic structure, overview. Coexpressions of the PDOR and GDHt from gene dhaB in Klebsiella pneumoniae result in an increase of molar yield from 50.6-64.0% of 1,3-propanediol | Clostridium butyricum |
gene dhaT, part of the dha regulon, genetic structure, recombinant expression in Escherichia coli | Citrobacter freundii |
gene dhaT, part of the dha regulon, genetic structure, recombinant expression in Escherichia coli | Clostridium perfringens |
gene dhaT, part of the dha regulon, genetic structure, recombinant expression in Escherichia coli | Thermotoga maritima |
gene dhaT, part of the dha regulon, recombinant expression in Escherichia coli | Klebsiella pneumoniae |
gene dhaT, part of the dha regulon, recombinant expression in Escherichia coli | Pantoea agglomerans |
gene dhaT, part of the dha regulon, recombinant expression in Escherichia coli | Clostridium pasteurianum |
gene dhaT, part of the dha regulon, recombinant expression in Escherichia coli | Levilactobacillus brevis |
gene dhaT, part of the dha regulon, recombinant expression in Escherichia coli | Lentilactobacillus buchneri |
gene dhaT, part of the dha regulon, recombinant expression in Escherichia coli | Limosilactobacillus reuteri |
Protein Variants | Comment | Organism |
---|---|---|
additional information | the PDOR isozyme activity increases 4.6times, when the yqhD gene is expressed in the Klebsiella pneumoniae mutant strains AK, which is a knockout mutant of the GDH and PDOR | Klebsiella pneumoniae |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | activates | Levilactobacillus brevis | |
Ca2+ | activates | Lentilactobacillus buchneri | |
Fe2+ | required, activates | Klebsiella pneumoniae | |
Fe2+ | required, activates | Clostridium pasteurianum | |
Fe2+ | required, activates | Levilactobacillus brevis | |
Fe2+ | required, activates | Clostridium butyricum | |
Fe2+ | required, activates | Citrobacter freundii | |
Fe2+ | required, activates | Lentilactobacillus buchneri | |
Fe2+ | required, activates | Clostridium perfringens | |
Fe2+ | required, activates | Thermotoga maritima | |
Fe2+ | required, activates | Limosilactobacillus reuteri | |
K+ | activates | Limosilactobacillus reuteri | |
Li+ | activates | Clostridium butyricum | |
Mg2+ | activates | Levilactobacillus brevis | |
Mg2+ | activates | Lentilactobacillus buchneri | |
Mn2+ | activates | Klebsiella pneumoniae | |
Mn2+ | activates | Pantoea agglomerans | |
Mn2+ | activates | Clostridium pasteurianum | |
Mn2+ | activates | Levilactobacillus brevis | |
Mn2+ | activates | Clostridium butyricum | |
Mn2+ | activates | Citrobacter freundii | |
Mn2+ | activates | Lentilactobacillus buchneri | |
Mn2+ | activates | Clostridium perfringens | |
Mn2+ | activates | Thermotoga maritima | |
Mn2+ | activates | Limosilactobacillus reuteri | |
additional information | the highest enzyme activity occurs with Mn2+, while the enzyme activity declines by 60-90% with other cations | Clostridium pasteurianum | |
additional information | the highest enzyme activity occurs with Mn2+, while the enzyme activity declines by 60-90% with other cations | Clostridium butyricum | |
Na+ | activates | Klebsiella pneumoniae | |
Na+ | activates | Clostridium butyricum | |
NH4+ | activates | Klebsiella pneumoniae |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
38500 | - |
- |
Pantoea agglomerans |
41500 | - |
- |
Klebsiella pneumoniae |
42000 | - |
x * 42000 | Klebsiella pneumoniae |
42000 | - |
x * 42000 | Clostridium butyricum |
43400 | - |
- |
Citrobacter freundii |
336000 | - |
- |
Klebsiella pneumoniae |
347000 | - |
- |
Citrobacter freundii |
350000 | - |
- |
Levilactobacillus brevis |
355000 | - |
- |
Pantoea agglomerans |
384200 | - |
- |
Clostridium butyricum |
387000 | - |
- |
Klebsiella pneumoniae |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
1,2-propylene glycol + NAD+ | Klebsiella pneumoniae | - |
? + NADH + H+ | - |
r | |
1,2-propylene glycol + NAD+ | Pantoea agglomerans | - |
? + NADH + H+ | - |
r | |
1,2-propylene glycol + NAD+ | Clostridium pasteurianum | - |
? + NADH + H+ | - |
r | |
1,2-propylene glycol + NAD+ | Levilactobacillus brevis | - |
? + NADH + H+ | - |
r | |
1,2-propylene glycol + NAD+ | Clostridium butyricum | - |
? + NADH + H+ | - |
r | |
1,2-propylene glycol + NAD+ | Citrobacter freundii | - |
? + NADH + H+ | - |
r | |
1,2-propylene glycol + NAD+ | Lentilactobacillus buchneri | - |
? + NADH + H+ | - |
r | |
1,2-propylene glycol + NAD+ | Clostridium perfringens | - |
? + NADH + H+ | - |
r | |
1,2-propylene glycol + NAD+ | Thermotoga maritima | - |
? + NADH + H+ | - |
r | |
1,2-propylene glycol + NAD+ | Limosilactobacillus reuteri | - |
? + NADH + H+ | - |
r | |
1,2-propylene glycol + NAD+ | Citrobacter freundii DSM 30040 | - |
? + NADH + H+ | - |
r | |
1,2-propylene glycol + NAD+ | Klebsiella pneumoniae DSM2026 | - |
? + NADH + H+ | - |
r | |
1,4-butanediol + NAD+ | Klebsiella pneumoniae | - |
4-hydroxybutanal + NADH + H+ | - |
r | |
1,4-butanediol + NAD+ | Pantoea agglomerans | - |
4-hydroxybutanal + NADH + H+ | - |
r | |
1,4-butanediol + NAD+ | Clostridium pasteurianum | - |
4-hydroxybutanal + NADH + H+ | - |
r | |
1,4-butanediol + NAD+ | Levilactobacillus brevis | - |
4-hydroxybutanal + NADH + H+ | - |
r | |
1,4-butanediol + NAD+ | Clostridium butyricum | - |
4-hydroxybutanal + NADH + H+ | - |
r | |
1,4-butanediol + NAD+ | Citrobacter freundii | - |
4-hydroxybutanal + NADH + H+ | - |
r | |
1,4-butanediol + NAD+ | Lentilactobacillus buchneri | - |
4-hydroxybutanal + NADH + H+ | - |
r | |
1,4-butanediol + NAD+ | Clostridium perfringens | - |
4-hydroxybutanal + NADH + H+ | - |
r | |
1,4-butanediol + NAD+ | Thermotoga maritima | - |
4-hydroxybutanal + NADH + H+ | - |
r | |
1,4-butanediol + NAD+ | Limosilactobacillus reuteri | - |
4-hydroxybutanal + NADH + H+ | - |
r | |
1-butyl alcohol + NAD+ | Klebsiella pneumoniae | - |
1-butanal + NADH + H+ | - |
r | |
1-butyl alcohol + NAD+ | Pantoea agglomerans | - |
1-butanal + NADH + H+ | - |
r | |
1-butyl alcohol + NAD+ | Clostridium pasteurianum | - |
1-butanal + NADH + H+ | - |
r | |
1-butyl alcohol + NAD+ | Levilactobacillus brevis | - |
1-butanal + NADH + H+ | - |
r | |
1-butyl alcohol + NAD+ | Clostridium butyricum | - |
1-butanal + NADH + H+ | - |
r | |
1-butyl alcohol + NAD+ | Citrobacter freundii | - |
1-butanal + NADH + H+ | - |
r | |
1-butyl alcohol + NAD+ | Lentilactobacillus buchneri | - |
1-butanal + NADH + H+ | - |
r | |
1-butyl alcohol + NAD+ | Clostridium perfringens | - |
1-butanal + NADH + H+ | - |
r | |
1-butyl alcohol + NAD+ | Thermotoga maritima | - |
1-butanal + NADH + H+ | - |
r | |
1-butyl alcohol + NAD+ | Limosilactobacillus reuteri | - |
1-butanal + NADH + H+ | - |
r | |
1-propanol + NAD+ | Klebsiella pneumoniae | - |
propanal + NADH + H+ | - |
r | |
1-propanol + NAD+ | Pantoea agglomerans | - |
propanal + NADH + H+ | - |
r | |
1-propanol + NAD+ | Clostridium pasteurianum | - |
propanal + NADH + H+ | - |
r | |
1-propanol + NAD+ | Levilactobacillus brevis | - |
propanal + NADH + H+ | - |
r | |
1-propanol + NAD+ | Clostridium butyricum | - |
propanal + NADH + H+ | - |
r | |
1-propanol + NAD+ | Citrobacter freundii | - |
propanal + NADH + H+ | - |
r | |
1-propanol + NAD+ | Lentilactobacillus buchneri | - |
propanal + NADH + H+ | - |
r | |
1-propanol + NAD+ | Clostridium perfringens | - |
propanal + NADH + H+ | - |
r | |
1-propanol + NAD+ | Thermotoga maritima | - |
propanal + NADH + H+ | - |
r | |
1-propanol + NAD+ | Limosilactobacillus reuteri | - |
propanal + NADH + H+ | - |
r | |
1-propanol + NAD+ | Clostridium butyricum E5 | - |
propanal + NADH + H+ | - |
r | |
1-propanol + NAD+ | Citrobacter freundii DSM 30040 | - |
propanal + NADH + H+ | - |
r | |
1-propanol + NAD+ | Klebsiella pneumoniae DSM2026 | - |
propanal + NADH + H+ | - |
r | |
glycerol + NAD+ | Klebsiella pneumoniae | - |
glyceraldehyde + NADH + H+ | - |
r | |
glycerol + NAD+ | Pantoea agglomerans | - |
glyceraldehyde + NADH + H+ | - |
r | |
glycerol + NAD+ | Clostridium pasteurianum | - |
glyceraldehyde + NADH + H+ | - |
r | |
glycerol + NAD+ | Levilactobacillus brevis | - |
glyceraldehyde + NADH + H+ | - |
r | |
glycerol + NAD+ | Clostridium butyricum | - |
glyceraldehyde + NADH + H+ | - |
r | |
glycerol + NAD+ | Citrobacter freundii | - |
glyceraldehyde + NADH + H+ | - |
r | |
glycerol + NAD+ | Lentilactobacillus buchneri | - |
glyceraldehyde + NADH + H+ | - |
r | |
glycerol + NAD+ | Clostridium perfringens | - |
glyceraldehyde + NADH + H+ | - |
r | |
glycerol + NAD+ | Thermotoga maritima | - |
glyceraldehyde + NADH + H+ | - |
r | |
glycerol + NAD+ | Limosilactobacillus reuteri | - |
glyceraldehyde + NADH + H+ | - |
r | |
glycerol + NAD+ | Clostridium butyricum E5 | - |
glyceraldehyde + NADH + H+ | - |
r | |
glycerol + NAD+ | Citrobacter freundii DSM 30040 | - |
glyceraldehyde + NADH + H+ | - |
r | |
glycerol + NAD+ | Klebsiella pneumoniae DSM2026 | - |
glyceraldehyde + NADH + H+ | - |
r | |
additional information | Clostridium pasteurianum | the enzyme can also use 1,4-butanediol, 1-butyl alcohol, 1-propanol, glycerol, or 1,2-propylene glycol as substrate. The optimal substrate is 3-hydroxypropanal in the catalytic reduction reaction, and the optimal substrate is propane-1,3-diol in the catalytic oxidation reaction | ? | - |
? | |
additional information | Clostridium butyricum | the enzyme can also use 1,4-butanediol, 1-butyl alcohol, 1-propanol, glycerol, or 1,2-propylene glycol as substrate. The optimal substrate is 3-hydroxypropanal in the catalytic reduction reaction, and the optimal substrate is propane-1,3-diol in the catalytic oxidation reaction | ? | - |
? | |
additional information | Clostridium butyricum E5 | the enzyme can also use 1,4-butanediol, 1-butyl alcohol, 1-propanol, glycerol, or 1,2-propylene glycol as substrate. The optimal substrate is 3-hydroxypropanal in the catalytic reduction reaction, and the optimal substrate is propane-1,3-diol in the catalytic oxidation reaction | ? | - |
? | |
propane-1,3-diol + NAD+ | Klebsiella pneumoniae | - |
3-hydroxypropanal + NADH + H+ | - |
r | |
propane-1,3-diol + NAD+ | Pantoea agglomerans | - |
3-hydroxypropanal + NADH + H+ | - |
r | |
propane-1,3-diol + NAD+ | Clostridium pasteurianum | - |
3-hydroxypropanal + NADH + H+ | - |
r | |
propane-1,3-diol + NAD+ | Levilactobacillus brevis | - |
3-hydroxypropanal + NADH + H+ | - |
r | |
propane-1,3-diol + NAD+ | Clostridium butyricum | - |
3-hydroxypropanal + NADH + H+ | - |
r | |
propane-1,3-diol + NAD+ | Citrobacter freundii | - |
3-hydroxypropanal + NADH + H+ | - |
r | |
propane-1,3-diol + NAD+ | Lentilactobacillus buchneri | - |
3-hydroxypropanal + NADH + H+ | - |
r | |
propane-1,3-diol + NAD+ | Clostridium perfringens | - |
3-hydroxypropanal + NADH + H+ | - |
r | |
propane-1,3-diol + NAD+ | Thermotoga maritima | - |
3-hydroxypropanal + NADH + H+ | - |
r | |
propane-1,3-diol + NAD+ | Limosilactobacillus reuteri | - |
3-hydroxypropanal + NADH + H+ | - |
r | |
propane-1,3-diol + NAD+ | Clostridium butyricum E5 | - |
3-hydroxypropanal + NADH + H+ | - |
r | |
propane-1,3-diol + NAD+ | Citrobacter freundii DSM 30040 | - |
3-hydroxypropanal + NADH + H+ | - |
r | |
propane-1,3-diol + NAD+ | Klebsiella pneumoniae DSM2026 | - |
3-hydroxypropanal + NADH + H+ | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Citrobacter freundii | - |
- |
- |
Citrobacter freundii DSM 30040 | - |
- |
- |
Clostridium butyricum | - |
- |
- |
Clostridium butyricum E5 | - |
- |
- |
Clostridium pasteurianum | - |
- |
- |
Clostridium perfringens | - |
- |
- |
Klebsiella pneumoniae | - |
- |
- |
Klebsiella pneumoniae DSM2026 | - |
- |
- |
Lentilactobacillus buchneri | - |
- |
- |
Levilactobacillus brevis | - |
- |
- |
Limosilactobacillus reuteri | - |
- |
- |
Pantoea agglomerans | - |
- |
- |
Thermotoga maritima | - |
- |
- |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
3.42 | - |
pH and temperature not specified in the publication | Pantoea agglomerans |
4.51 | - |
pH and temperature not specified in the publication | Clostridium butyricum |
7.28 | - |
pH and temperature not specified in the publication | Levilactobacillus brevis |
9.85 | - |
pH and temperature not specified in the publication | Klebsiella pneumoniae |
11 | - |
pH and temperature not specified in the publication | Citrobacter freundii |
37 | - |
pH and temperature not specified in the publication | Klebsiella pneumoniae |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
1,2-propylene glycol + NAD+ | - |
Klebsiella pneumoniae | ? + NADH + H+ | - |
r | |
1,2-propylene glycol + NAD+ | - |
Pantoea agglomerans | ? + NADH + H+ | - |
r | |
1,2-propylene glycol + NAD+ | - |
Clostridium pasteurianum | ? + NADH + H+ | - |
r | |
1,2-propylene glycol + NAD+ | - |
Levilactobacillus brevis | ? + NADH + H+ | - |
r | |
1,2-propylene glycol + NAD+ | - |
Clostridium butyricum | ? + NADH + H+ | - |
r | |
1,2-propylene glycol + NAD+ | - |
Citrobacter freundii | ? + NADH + H+ | - |
r | |
1,2-propylene glycol + NAD+ | - |
Lentilactobacillus buchneri | ? + NADH + H+ | - |
r | |
1,2-propylene glycol + NAD+ | - |
Clostridium perfringens | ? + NADH + H+ | - |
r | |
1,2-propylene glycol + NAD+ | - |
Thermotoga maritima | ? + NADH + H+ | - |
r | |
1,2-propylene glycol + NAD+ | - |
Limosilactobacillus reuteri | ? + NADH + H+ | - |
r | |
1,2-propylene glycol + NAD+ | - |
Citrobacter freundii DSM 30040 | ? + NADH + H+ | - |
r | |
1,2-propylene glycol + NAD+ | - |
Klebsiella pneumoniae DSM2026 | ? + NADH + H+ | - |
r | |
1,4-butanediol + NAD+ | - |
Klebsiella pneumoniae | 4-hydroxybutanal + NADH + H+ | - |
r | |
1,4-butanediol + NAD+ | - |
Pantoea agglomerans | 4-hydroxybutanal + NADH + H+ | - |
r | |
1,4-butanediol + NAD+ | - |
Clostridium pasteurianum | 4-hydroxybutanal + NADH + H+ | - |
r | |
1,4-butanediol + NAD+ | - |
Levilactobacillus brevis | 4-hydroxybutanal + NADH + H+ | - |
r | |
1,4-butanediol + NAD+ | - |
Clostridium butyricum | 4-hydroxybutanal + NADH + H+ | - |
r | |
1,4-butanediol + NAD+ | - |
Citrobacter freundii | 4-hydroxybutanal + NADH + H+ | - |
r | |
1,4-butanediol + NAD+ | - |
Lentilactobacillus buchneri | 4-hydroxybutanal + NADH + H+ | - |
r | |
1,4-butanediol + NAD+ | - |
Clostridium perfringens | 4-hydroxybutanal + NADH + H+ | - |
r | |
1,4-butanediol + NAD+ | - |
Thermotoga maritima | 4-hydroxybutanal + NADH + H+ | - |
r | |
1,4-butanediol + NAD+ | - |
Limosilactobacillus reuteri | 4-hydroxybutanal + NADH + H+ | - |
r | |
1-butyl alcohol + NAD+ | - |
Klebsiella pneumoniae | 1-butanal + NADH + H+ | - |
r | |
1-butyl alcohol + NAD+ | - |
Pantoea agglomerans | 1-butanal + NADH + H+ | - |
r | |
1-butyl alcohol + NAD+ | - |
Clostridium pasteurianum | 1-butanal + NADH + H+ | - |
r | |
1-butyl alcohol + NAD+ | - |
Levilactobacillus brevis | 1-butanal + NADH + H+ | - |
r | |
1-butyl alcohol + NAD+ | - |
Clostridium butyricum | 1-butanal + NADH + H+ | - |
r | |
1-butyl alcohol + NAD+ | - |
Citrobacter freundii | 1-butanal + NADH + H+ | - |
r | |
1-butyl alcohol + NAD+ | - |
Lentilactobacillus buchneri | 1-butanal + NADH + H+ | - |
r | |
1-butyl alcohol + NAD+ | - |
Clostridium perfringens | 1-butanal + NADH + H+ | - |
r | |
1-butyl alcohol + NAD+ | - |
Thermotoga maritima | 1-butanal + NADH + H+ | - |
r | |
1-butyl alcohol + NAD+ | - |
Limosilactobacillus reuteri | 1-butanal + NADH + H+ | - |
r | |
1-propanol + NAD+ | - |
Klebsiella pneumoniae | propanal + NADH + H+ | - |
r | |
1-propanol + NAD+ | - |
Pantoea agglomerans | propanal + NADH + H+ | - |
r | |
1-propanol + NAD+ | - |
Clostridium pasteurianum | propanal + NADH + H+ | - |
r | |
1-propanol + NAD+ | - |
Levilactobacillus brevis | propanal + NADH + H+ | - |
r | |
1-propanol + NAD+ | - |
Clostridium butyricum | propanal + NADH + H+ | - |
r | |
1-propanol + NAD+ | - |
Citrobacter freundii | propanal + NADH + H+ | - |
r | |
1-propanol + NAD+ | - |
Lentilactobacillus buchneri | propanal + NADH + H+ | - |
r | |
1-propanol + NAD+ | - |
Clostridium perfringens | propanal + NADH + H+ | - |
r | |
1-propanol + NAD+ | - |
Thermotoga maritima | propanal + NADH + H+ | - |
r | |
1-propanol + NAD+ | - |
Limosilactobacillus reuteri | propanal + NADH + H+ | - |
r | |
1-propanol + NAD+ | - |
Clostridium butyricum E5 | propanal + NADH + H+ | - |
r | |
1-propanol + NAD+ | - |
Citrobacter freundii DSM 30040 | propanal + NADH + H+ | - |
r | |
1-propanol + NAD+ | - |
Klebsiella pneumoniae DSM2026 | propanal + NADH + H+ | - |
r | |
3-hydroxypropanal + NADH + H+ | - |
Klebsiella pneumoniae | propane-1,3-diol + NAD+ | - |
r | |
3-hydroxypropanal + NADH + H+ | - |
Pantoea agglomerans | propane-1,3-diol + NAD+ | - |
r | |
3-hydroxypropanal + NADH + H+ | - |
Clostridium pasteurianum | propane-1,3-diol + NAD+ | - |
r | |
3-hydroxypropanal + NADH + H+ | - |
Levilactobacillus brevis | propane-1,3-diol + NAD+ | - |
r | |
3-hydroxypropanal + NADH + H+ | - |
Clostridium butyricum | propane-1,3-diol + NAD+ | - |
r | |
3-hydroxypropanal + NADH + H+ | - |
Citrobacter freundii | propane-1,3-diol + NAD+ | - |
r | |
3-hydroxypropanal + NADH + H+ | - |
Lentilactobacillus buchneri | propane-1,3-diol + NAD+ | - |
r | |
3-hydroxypropanal + NADH + H+ | - |
Clostridium perfringens | propane-1,3-diol + NAD+ | - |
r | |
3-hydroxypropanal + NADH + H+ | - |
Thermotoga maritima | propane-1,3-diol + NAD+ | - |
r | |
3-hydroxypropanal + NADH + H+ | - |
Limosilactobacillus reuteri | propane-1,3-diol + NAD+ | - |
r | |
3-hydroxypropanal + NADH + H+ | - |
Clostridium butyricum E5 | propane-1,3-diol + NAD+ | - |
r | |
3-hydroxypropanal + NADH + H+ | - |
Citrobacter freundii DSM 30040 | propane-1,3-diol + NAD+ | - |
r | |
3-hydroxypropanal + NADH + H+ | - |
Klebsiella pneumoniae DSM2026 | propane-1,3-diol + NAD+ | - |
r | |
glycerol + NAD+ | - |
Klebsiella pneumoniae | glyceraldehyde + NADH + H+ | - |
r | |
glycerol + NAD+ | - |
Pantoea agglomerans | glyceraldehyde + NADH + H+ | - |
r | |
glycerol + NAD+ | - |
Clostridium pasteurianum | glyceraldehyde + NADH + H+ | - |
r | |
glycerol + NAD+ | - |
Levilactobacillus brevis | glyceraldehyde + NADH + H+ | - |
r | |
glycerol + NAD+ | - |
Clostridium butyricum | glyceraldehyde + NADH + H+ | - |
r | |
glycerol + NAD+ | - |
Citrobacter freundii | glyceraldehyde + NADH + H+ | - |
r | |
glycerol + NAD+ | - |
Lentilactobacillus buchneri | glyceraldehyde + NADH + H+ | - |
r | |
glycerol + NAD+ | - |
Clostridium perfringens | glyceraldehyde + NADH + H+ | - |
r | |
glycerol + NAD+ | - |
Thermotoga maritima | glyceraldehyde + NADH + H+ | - |
r | |
glycerol + NAD+ | - |
Limosilactobacillus reuteri | glyceraldehyde + NADH + H+ | - |
r | |
glycerol + NAD+ | - |
Clostridium butyricum E5 | glyceraldehyde + NADH + H+ | - |
r | |
glycerol + NAD+ | - |
Citrobacter freundii DSM 30040 | glyceraldehyde + NADH + H+ | - |
r | |
glycerol + NAD+ | - |
Klebsiella pneumoniae DSM2026 | glyceraldehyde + NADH + H+ | - |
r | |
additional information | the enzyme can also use 1,4-butanediol, 1-butyl alcohol, 1-propanol, glycerol, or 1,2-propylene glycol as substrate. The optimal substrate is 3-hydroxypropanal in the catalytic reduction reaction, and the optimal substrate is propane-1,3-diol in the catalytic oxidation reaction | Clostridium pasteurianum | ? | - |
? | |
additional information | the enzyme can also use 1,4-butanediol, 1-butyl alcohol, 1-propanol, glycerol, or 1,2-propylene glycol as substrate. The optimal substrate is 3-hydroxypropanal in the catalytic reduction reaction, and the optimal substrate is propane-1,3-diol in the catalytic oxidation reaction | Clostridium butyricum | ? | - |
? | |
additional information | the enzyme can also use 1,4-butanediol, 1-butyl alcohol, 1-propanol, glycerol, or 1,2-propylene glycol as substrate. The optimal substrate is 3-hydroxypropanal in the catalytic reduction reaction, and the optimal substrate is propane-1,3-diol in the catalytic oxidation reaction | Clostridium butyricum E5 | ? | - |
? | |
propane-1,3-diol + NAD+ | - |
Klebsiella pneumoniae | 3-hydroxypropanal + NADH + H+ | - |
r | |
propane-1,3-diol + NAD+ | - |
Pantoea agglomerans | 3-hydroxypropanal + NADH + H+ | - |
r | |
propane-1,3-diol + NAD+ | - |
Clostridium pasteurianum | 3-hydroxypropanal + NADH + H+ | - |
r | |
propane-1,3-diol + NAD+ | - |
Levilactobacillus brevis | 3-hydroxypropanal + NADH + H+ | - |
r | |
propane-1,3-diol + NAD+ | - |
Clostridium butyricum | 3-hydroxypropanal + NADH + H+ | - |
r | |
propane-1,3-diol + NAD+ | - |
Citrobacter freundii | 3-hydroxypropanal + NADH + H+ | - |
r | |
propane-1,3-diol + NAD+ | - |
Lentilactobacillus buchneri | 3-hydroxypropanal + NADH + H+ | - |
r | |
propane-1,3-diol + NAD+ | - |
Clostridium perfringens | 3-hydroxypropanal + NADH + H+ | - |
r | |
propane-1,3-diol + NAD+ | - |
Thermotoga maritima | 3-hydroxypropanal + NADH + H+ | - |
r | |
propane-1,3-diol + NAD+ | - |
Limosilactobacillus reuteri | 3-hydroxypropanal + NADH + H+ | - |
r | |
propane-1,3-diol + NAD+ | - |
Clostridium butyricum E5 | 3-hydroxypropanal + NADH + H+ | - |
r | |
propane-1,3-diol + NAD+ | - |
Citrobacter freundii DSM 30040 | 3-hydroxypropanal + NADH + H+ | - |
r | |
propane-1,3-diol + NAD+ | - |
Klebsiella pneumoniae DSM2026 | 3-hydroxypropanal + NADH + H+ | - |
r |
Subunits | Comment | Organism |
---|---|---|
oligomer | x * 42000 | Klebsiella pneumoniae |
oligomer | x * 42000 | Clostridium butyricum |
oligomer | x * 38500 | Pantoea agglomerans |
oligomer | x * 41000-46000 | Levilactobacillus brevis |
oligomer | x * 41500 | Klebsiella pneumoniae |
oligomer | x * 43400 | Citrobacter freundii |
Synonyms | Comment | Organism |
---|---|---|
1,3-propanediol-oxydoreductase | - |
Klebsiella pneumoniae |
1,3-propanediol-oxydoreductase | - |
Pantoea agglomerans |
1,3-propanediol-oxydoreductase | - |
Clostridium pasteurianum |
1,3-propanediol-oxydoreductase | - |
Levilactobacillus brevis |
1,3-propanediol-oxydoreductase | - |
Clostridium butyricum |
1,3-propanediol-oxydoreductase | - |
Citrobacter freundii |
1,3-propanediol-oxydoreductase | - |
Lentilactobacillus buchneri |
1,3-propanediol-oxydoreductase | - |
Clostridium perfringens |
1,3-propanediol-oxydoreductase | - |
Thermotoga maritima |
1,3-propanediol-oxydoreductase | - |
Limosilactobacillus reuteri |
DhaT | - |
Klebsiella pneumoniae |
DhaT | - |
Pantoea agglomerans |
DhaT | - |
Clostridium pasteurianum |
DhaT | - |
Levilactobacillus brevis |
DhaT | - |
Clostridium butyricum |
DhaT | - |
Citrobacter freundii |
DhaT | - |
Lentilactobacillus buchneri |
DhaT | - |
Clostridium perfringens |
DhaT | - |
Thermotoga maritima |
DhaT | - |
Limosilactobacillus reuteri |
PDOR | - |
Klebsiella pneumoniae |
PDOR | - |
Pantoea agglomerans |
PDOR | - |
Clostridium pasteurianum |
PDOR | - |
Levilactobacillus brevis |
PDOR | - |
Clostridium butyricum |
PDOR | - |
Citrobacter freundii |
PDOR | - |
Lentilactobacillus buchneri |
PDOR | - |
Clostridium perfringens |
PDOR | - |
Thermotoga maritima |
PDOR | - |
Limosilactobacillus reuteri |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
30 | - |
- |
Klebsiella pneumoniae |
37 | - |
- |
Pantoea agglomerans |
37 | - |
- |
Levilactobacillus brevis |
37 | - |
- |
Clostridium butyricum |
37 | - |
- |
Citrobacter freundii |
55 | - |
- |
Klebsiella pneumoniae |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6.6 | - |
aldehyde reduction | Clostridium pasteurianum |
6.6 | - |
aldehyde reduction | Levilactobacillus brevis |
6.6 | - |
aldehyde reduction | Clostridium butyricum |
6.6 | - |
aldehyde reduction | Lentilactobacillus buchneri |
6.6 | - |
aldehyde reduction | Limosilactobacillus reuteri |
7.7 | - |
- |
Citrobacter freundii |
7.8 | - |
- |
Pantoea agglomerans |
9 | - |
alcohol oxidation | Clostridium pasteurianum |
9 | - |
alcohol oxidation | Lentilactobacillus buchneri |
9 | - |
alcohol oxidation | Limosilactobacillus reuteri |
9.1 | - |
alcohol oxidation | Clostridium butyricum |
9.5 | - |
alcohol oxidation | Klebsiella pneumoniae |
10 | - |
alcohol oxidation | Klebsiella pneumoniae |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Klebsiella pneumoniae | |
NAD+ | - |
Pantoea agglomerans | |
NAD+ | - |
Clostridium pasteurianum | |
NAD+ | - |
Levilactobacillus brevis | |
NAD+ | - |
Clostridium butyricum | |
NAD+ | - |
Citrobacter freundii | |
NAD+ | - |
Lentilactobacillus buchneri | |
NAD+ | - |
Clostridium perfringens | |
NAD+ | - |
Thermotoga maritima | |
NAD+ | - |
Limosilactobacillus reuteri | |
NADH | - |
Klebsiella pneumoniae | |
NADH | - |
Pantoea agglomerans | |
NADH | - |
Clostridium pasteurianum | |
NADH | - |
Levilactobacillus brevis | |
NADH | - |
Clostridium butyricum | |
NADH | - |
Citrobacter freundii | |
NADH | - |
Lentilactobacillus buchneri | |
NADH | - |
Clostridium perfringens | |
NADH | - |
Thermotoga maritima | |
NADH | - |
Limosilactobacillus reuteri |
General Information | Comment | Organism |
---|---|---|
evolution | PDOR belongs to the Fe-NAD-dependent alcohol dehydrogenase third family, and it is also a typical iron-ion activation-type dehydrogenase | Klebsiella pneumoniae |
evolution | PDOR belongs to the Fe-NAD-dependent alcohol dehydrogenase third family, and it is also a typical iron-ion activation-type dehydrogenase | Pantoea agglomerans |
evolution | PDOR belongs to the Fe-NAD-dependent alcohol dehydrogenase third family, and it is also a typical iron-ion activation-type dehydrogenase | Clostridium pasteurianum |
evolution | PDOR belongs to the Fe-NAD-dependent alcohol dehydrogenase third family, and it is also a typical iron-ion activation-type dehydrogenase | Levilactobacillus brevis |
evolution | PDOR belongs to the Fe-NAD-dependent alcohol dehydrogenase third family, and it is also a typical iron-ion activation-type dehydrogenase | Clostridium butyricum |
evolution | PDOR belongs to the Fe-NAD-dependent alcohol dehydrogenase third family, and it is also a typical iron-ion activation-type dehydrogenase | Citrobacter freundii |
evolution | PDOR belongs to the Fe-NAD-dependent alcohol dehydrogenase third family, and it is also a typical iron-ion activation-type dehydrogenase | Lentilactobacillus buchneri |
evolution | PDOR belongs to the Fe-NAD-dependent alcohol dehydrogenase third family, and it is also a typical iron-ion activation-type dehydrogenase | Clostridium perfringens |
evolution | PDOR belongs to the Fe-NAD-dependent alcohol dehydrogenase third family, and it is also a typical iron-ion activation-type dehydrogenase | Thermotoga maritima |
evolution | PDOR belongs to the Fe-NAD-dependent alcohol dehydrogenase third family, and it is also a typical iron-ion activation-type dehydrogenase | Limosilactobacillus reuteri |
malfunction | accumulation of 3-HPA can inhibit the activity of glycerol dehydratase to prevent the growth of bacteria and result in reducing the production of propane-1,3-diol, leading to a major influence in the production of propane-1,3-diol | Clostridium pasteurianum |
malfunction | accumulation of 3-hydroxypropanal can inhibit the activity of glycerol dehydratase to prevent the growth of bacteria and result in reducing the production of propane-1,3-diol, leading to a major influence in the production of propane-1,3-diol | Klebsiella pneumoniae |
malfunction | accumulation of 3-hydroxypropanal can inhibit the activity of glycerol dehydratase to prevent the growth of bacteria and result in reducing the production of propane-1,3-diol, leading to a major influence in the production of propane-1,3-diol | Pantoea agglomerans |
malfunction | accumulation of 3-hydroxypropanal can inhibit the activity of glycerol dehydratase to prevent the growth of bacteria and result in reducing the production of propane-1,3-diol, leading to a major influence in the production of propane-1,3-diol | Levilactobacillus brevis |
malfunction | accumulation of 3-hydroxypropanal can inhibit the activity of glycerol dehydratase to prevent the growth of bacteria and result in reducing the production of propane-1,3-diol, leading to a major influence in the production of propane-1,3-diol | Clostridium butyricum |
malfunction | accumulation of 3-hydroxypropanal can inhibit the activity of glycerol dehydratase to prevent the growth of bacteria and result in reducing the production of propane-1,3-diol, leading to a major influence in the production of propane-1,3-diol | Citrobacter freundii |
malfunction | accumulation of 3-hydroxypropanal can inhibit the activity of glycerol dehydratase to prevent the growth of bacteria and result in reducing the production of propane-1,3-diol, leading to a major influence in the production of propane-1,3-diol | Lentilactobacillus buchneri |
malfunction | accumulation of 3-hydroxypropanal can inhibit the activity of glycerol dehydratase to prevent the growth of bacteria and result in reducing the production of propane-1,3-diol, leading to a major influence in the production of propane-1,3-diol | Clostridium perfringens |
malfunction | accumulation of 3-hydroxypropanal can inhibit the activity of glycerol dehydratase to prevent the growth of bacteria and result in reducing the production of propane-1,3-diol, leading to a major influence in the production of propane-1,3-diol | Thermotoga maritima |
malfunction | accumulation of 3-hydroxypropanal can inhibit the activity of glycerol dehydratase to prevent the growth of bacteria and result in reducing the production of propane-1,3-diol, leading to a major influence in the production of propane-1,3-diol | Limosilactobacillus reuteri |
metabolism | glycerol dehydratase, 1,3-propanediol dehydrogenase, and glycerol dehydrogenase are key enzymes in glycerol bioconversion into 1,3-propanediol and dihydroxyacetone | Klebsiella pneumoniae |
metabolism | glycerol dehydratase, 1,3-propanediol dehydrogenase, and glycerol dehydrogenase are key enzymes in glycerol bioconversion into 1,3-propanediol and dihydroxyacetone | Pantoea agglomerans |
metabolism | glycerol dehydratase, 1,3-propanediol dehydrogenase, and glycerol dehydrogenase are key enzymes in glycerol bioconversion into 1,3-propanediol and dihydroxyacetone | Clostridium pasteurianum |
metabolism | glycerol dehydratase, 1,3-propanediol dehydrogenase, and glycerol dehydrogenase are key enzymes in glycerol bioconversion into 1,3-propanediol and dihydroxyacetone | Levilactobacillus brevis |
metabolism | glycerol dehydratase, 1,3-propanediol dehydrogenase, and glycerol dehydrogenase are key enzymes in glycerol bioconversion into 1,3-propanediol and dihydroxyacetone | Clostridium butyricum |
metabolism | glycerol dehydratase, 1,3-propanediol dehydrogenase, and glycerol dehydrogenase are key enzymes in glycerol bioconversion into 1,3-propanediol and dihydroxyacetone | Citrobacter freundii |
metabolism | glycerol dehydratase, 1,3-propanediol dehydrogenase, and glycerol dehydrogenase are key enzymes in glycerol bioconversion into 1,3-propanediol and dihydroxyacetone | Lentilactobacillus buchneri |
metabolism | glycerol dehydratase, 1,3-propanediol dehydrogenase, and glycerol dehydrogenase are key enzymes in glycerol bioconversion into 1,3-propanediol and dihydroxyacetone | Clostridium perfringens |
metabolism | glycerol dehydratase, 1,3-propanediol dehydrogenase, and glycerol dehydrogenase are key enzymes in glycerol bioconversion into 1,3-propanediol and dihydroxyacetone | Thermotoga maritima |
metabolism | glycerol dehydratase, 1,3-propanediol dehydrogenase, and glycerol dehydrogenase are key enzymes in glycerol bioconversion into 1,3-propanediol and dihydroxyacetone | Limosilactobacillus reuteri |