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Literature summary for 1.1.1.2 extracted from

  • Bronaugh, R.L.; Erwin, V.
    Partial purification and characterization of NADPH-linked aldehyde reductase from monkey brain (1973), J. Neurochem., 21, 809-815.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
chlorpromazine
-
Platyrrhini
Diphenylhydantoin
-
Platyrrhini

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
6.1
-
3,4-dihydroxyphenylacetaldehyde
-
Platyrrhini
12
-
3,4-dihydroxyphenylglycolaldehyde
-
Platyrrhini
27
-
5-Hydroxyindoleacetaldehyde
-
Platyrrhini

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
70000
-
gel filtration Platyrrhini

Organism

Organism UniProt Comment Textmining
Platyrrhini
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Platyrrhini

Source Tissue

Source Tissue Comment Organism Textmining
brain pons, medulla and midbrain Platyrrhini
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3,4-dihydroxyphenylacetaldehyde + NADPH + H+
-
Platyrrhini 3,4-dihydroxyphenylethanol + NADP+
-
r
3,4-dihydroxyphenylglycolaldehyde + NADPH
-
Platyrrhini ? + NADP+
-
r
5-hydroxyindoleacetaldehyde + NADPH
-
Platyrrhini ? + NADP+
-
?