Data extracted from this reference:
KM Value [mM]
0.005
NADPH
Escherichia coli
Molecular Weight [Da]
37000
gel filtration
Escherichia coli
Natural Substrates/ Products (Substrates)
5-amino-2,6-dioxy-4-(5'-phosphoribosylamino)pyrimidine + NADPH
Escherichia coli
intermediate in the biosynthesis of riboflavin
5-amino-2,6-dioxy-4-(5'-phosphoribitylamino)pyrimidine + NADP+
Escherichia coli
?
5-amino-2,6-dioxy-4-(5'-phosphoribosylamino)pyrimidine + NADPH
Escherichia coli B / ATCC 11303
intermediate in the biosynthesis of riboflavin
5-amino-2,6-dioxy-4-(5'-phosphoribitylamino)pyrimidine + NADP+
Escherichia coli B / ATCC 11303
?
Organism
Escherichia coli B / ATCC 11303
Purification (Commentary)
Source Tissue
cell culture
Escherichia coli
Storage Stability
-6°C, 50 mM Tris-HCl, pH 8.0, 1 month
Escherichia coli
Substrates and Products (Substrate)
5-amino-2,6-dioxy-4-(5'-phosphoribosylamino)pyrimidine + NADPH
intermediate in the biosynthesis of riboflavin
246736
Escherichia coli
5-amino-2,6-dioxy-4-(5'-phosphoribitylamino)pyrimidine + NADP+
246736
Escherichia coli
?
5-amino-2,6-dioxy-4-(5'-phosphoribosylamino)pyrimidine + NADPH
intermediate in the biosynthesis of riboflavin
246736
Escherichia coli B / ATCC 11303
5-amino-2,6-dioxy-4-(5'-phosphoribitylamino)pyrimidine + NADP+
246736
Escherichia coli B / ATCC 11303
?
pH Optimum
Cofactor
NADH
30% as effective as NADPH
Escherichia coli
Cofactor (protein specific)
NADH
30% as effective as NADPH
Escherichia coli
KM Value [mM] (protein specific)
0.005
NADPH
Escherichia coli
Molecular Weight [Da] (protein specific)
37000
gel filtration
Escherichia coli
Natural Substrates/ Products (Substrates) (protein specific)
5-amino-2,6-dioxy-4-(5'-phosphoribosylamino)pyrimidine + NADPH
Escherichia coli
intermediate in the biosynthesis of riboflavin
5-amino-2,6-dioxy-4-(5'-phosphoribitylamino)pyrimidine + NADP+
Escherichia coli
?
5-amino-2,6-dioxy-4-(5'-phosphoribosylamino)pyrimidine + NADPH
Escherichia coli B / ATCC 11303
intermediate in the biosynthesis of riboflavin
5-amino-2,6-dioxy-4-(5'-phosphoribitylamino)pyrimidine + NADP+
Escherichia coli B / ATCC 11303
?
Purification (Commentary) (protein specific)
Source Tissue (protein specific)
cell culture
Escherichia coli
Storage Stability (protein specific)
-6°C, 50 mM Tris-HCl, pH 8.0, 1 month
Escherichia coli
Substrates and Products (Substrate) (protein specific)
5-amino-2,6-dioxy-4-(5'-phosphoribosylamino)pyrimidine + NADPH
intermediate in the biosynthesis of riboflavin
246736
Escherichia coli
5-amino-2,6-dioxy-4-(5'-phosphoribitylamino)pyrimidine + NADP+
246736
Escherichia coli
?
5-amino-2,6-dioxy-4-(5'-phosphoribosylamino)pyrimidine + NADPH
intermediate in the biosynthesis of riboflavin
246736
Escherichia coli B / ATCC 11303
5-amino-2,6-dioxy-4-(5'-phosphoribitylamino)pyrimidine + NADP+
246736
Escherichia coli B / ATCC 11303
?
pH Optimum (protein specific)
Other publictions for EC 1.1.1.193
760492
Chen
Evolution of archaeal Rib7 an ...
Bacillus subtilis, Methanosarcina mazei
Biochem. Biophys. Res. Commun.
503
195-201
2018
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12
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723878
Dawson
Structure of diaminohydroxypho ...
Acinetobacter baumannii
Acta Crystallogr. Sect. F
69
611-617
2013
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1
1
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684754
Grill
Identification and characteriz ...
Streptomyces davaonensis, Streptomyces davaonensis 768
Arch. Microbiol.
188
377-387
2007
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1
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1
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4
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6
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4
1
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246735
Richter
Biosynthesis of riboflavin: ch ...
Bacillus subtilis, Escherichia coli
J. Bacteriol.
179
2022-2028
1997
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2
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2
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2
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2
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4
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4
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2
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246736
Burrows
Presence in Escherichia coli o ...
Escherichia coli, Escherichia coli B / ATCC 11303
J. Bacteriol.
136
657-667
1978
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1
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177
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