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Literature summary for 1.1.1.189 extracted from

  • Nakashima, K.; Ueno, N.; Kamei, D.; Tanioka, T.; Nakatani, Y.; Murakami, M.; Kudo, I.
    Coupling between cyclooxygenases and prostaglandin F(2alpha) synthase. Detection of an inducible, glutathione-activated, membrane-bound prostaglandin F2alpha-synthetic activity (2003), Biochim. Biophys. Acta, 1633, 96-105.
    View publication on PubMed
Search for more literature for 1.1.1.189

Activating Compound

Activating Compound Comment Organism Structure
lipopolysaccharides strong induction of the membrane-bound lung isozyme, significant induction in stomach, intestine, spleen, kidney, testis, and pancreas, overview Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Mus musculus 16020
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
prostaglandin H2 + NADPH + H+ Mus musculus
-
 prostaglandin F2alpha + NADP+
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Mus musculus
-
heart
-
 Mus musculus
-
intestine
-
 Mus musculus
-
kidney
-
 Mus musculus
-
liver
-
 Mus musculus
-
lung
-
 Mus musculus
-
pancreas
-
 Mus musculus
-
spleen
-
 Mus musculus
-
stomach
-
 Mus musculus
-
testis
-
 Mus musculus
-
thymus
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
prostaglandin H2 + NADPH + H+
-
 Mus musculus prostaglandin F2alpha + NADP+
-
 ?

Synonyms

Synonyms Comment Organism
mPGES
-
 Mus musculus

Cofactor

Cofactor Comment Organism Structure
NADPH
-
 Mus musculus