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Literature summary for 1.1.1.188 extracted from
- Two pathways for prostaglandin F2 alpha synthesis by the primate periovulatory follicle (2008), Reproduction, 136, 53-63.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| Gonadotropin | prostaglandin F synthase mRNA and protein levels are low before treatment with gonadotropin and peak 24-36 h after gonadotropin administration to granulosa cells | Macaca fascicularis |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | P42330 | AKR1C3 | - |
| Homo sapiens AKR1C3 | P42330 | AKR1C3 | - |
| Macaca fascicularis | - |
AKR1C3 | - |
| Macaca fascicularis AKR1C3 | - |
AKR1C3 | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| granulosa cell | both activities of enzymes AKR1C1/AKR1C2 and AKR1C3 are present in the periovuatory granulosa cell | Homo sapiens | - |
| granulosa cell | both activities of enzymes AKR1C1/AKR1C2 and AKR1C3 are present in the periovuatory granulosa cell. Prostaglandin F synthase mRNA and protein levels are low before treatment with gonadotropin and peak 24-36 h after gonadotropin administration | Macaca fascicularis | - |
| ovarian follicle | - |
Macaca fascicularis | - |
| ovarian follicle | - |
Homo sapiens | - |
| ovary | - |
Macaca fascicularis | - |
| ovary | - |
Homo sapiens | - |
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Release 2023.1 (January 2023)
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