Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Mus musculus | coupling ability between cyclooxygenase COX-2 and the prostanoid synthases performing the last stepes in the biosynthesis of prostaglandins PGE2, PGD2, PGF2alpha, and PGI2, regulation, overview, the 20alpha-hydroxysteroid dehydrogenase also shows prostaglandin F synthase activity in the endometrium during luteolysis | ? | - |
? | |
prostaglandin D2 + NADPH + H+ | Mus musculus | - |
9alpha,11alpha-prostaglandin F2alpha + NADP+ | - |
? | |
prostaglandin D2 + NADPH + H+ | Mus musculus | - |
9alpha,11beta-prostaglandin F2 + NADP+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
endometrium | during luteolysis, activity of 20alpha-hydroxysteroid dehydrogenase synthesizing prostaglandin F2alpha | Mus musculus | - |
liver | PGFS-II, liver-type isozyme | Mus musculus | - |
lung | PGFS-I, lung-type isozyme | Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | coupling ability between cyclooxygenase COX-2 and the prostanoid synthases performing the last stepes in the biosynthesis of prostaglandins PGE2, PGD2, PGF2alpha, and PGI2, regulation, overview, the 20alpha-hydroxysteroid dehydrogenase also shows prostaglandin F synthase activity in the endometrium during luteolysis | Mus musculus | ? | - |
? | |
prostaglandin D2 + NADPH + H+ | - |
Mus musculus | 9alpha,11alpha-prostaglandin F2alpha + NADP+ | - |
? | |
prostaglandin D2 + NADPH + H+ | - |
Mus musculus | 9alpha,11beta-prostaglandin F2 + NADP+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PGD 11-ketoreductase | - |
Mus musculus |
PGFS-I | - |
Mus musculus |
PGFS-II | - |
Mus musculus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | - |
Mus musculus |