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Literature summary for 1.1.1.188 extracted from

  • Ueno, N.; Takegoshi, Y.; Kamei, D.; Kudo, I.; Murakami, M.
    Coupling between cyclooxygenases and terminal prostanoid synthases (2005), Biochem. Biophys. Res. Commun., 338, 70-76.
    View publication on PubMed
Search for more literature for 1.1.1.188

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mus musculus coupling ability between cyclooxygenase COX-2 and the prostanoid synthases performing the last stepes in the biosynthesis of prostaglandins PGE2, PGD2, PGF2alpha, and PGI2, regulation, overview, the 20alpha-hydroxysteroid dehydrogenase also shows prostaglandin F synthase activity in the endometrium during luteolysis ?
-
 ?
prostaglandin D2 + NADPH + H+ Mus musculus
-
 9alpha,11alpha-prostaglandin F2alpha + NADP+
-
 ?
prostaglandin D2 + NADPH + H+ Mus musculus
-
 9alpha,11beta-prostaglandin F2 + NADP+
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
endometrium during luteolysis, activity of 20alpha-hydroxysteroid dehydrogenase synthesizing prostaglandin F2alpha Mus musculus
-
liver PGFS-II, liver-type isozyme Mus musculus
-
lung PGFS-I, lung-type isozyme Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information coupling ability between cyclooxygenase COX-2 and the prostanoid synthases performing the last stepes in the biosynthesis of prostaglandins PGE2, PGD2, PGF2alpha, and PGI2, regulation, overview, the 20alpha-hydroxysteroid dehydrogenase also shows prostaglandin F synthase activity in the endometrium during luteolysis Mus musculus ?
-
 ?
prostaglandin D2 + NADPH + H+
-
 Mus musculus 9alpha,11alpha-prostaglandin F2alpha + NADP+
-
 ?
prostaglandin D2 + NADPH + H+
-
 Mus musculus 9alpha,11beta-prostaglandin F2 + NADP+
-
 ?

Synonyms

Synonyms Comment Organism
PGD 11-ketoreductase
-
 Mus musculus
PGFS-I
-
 Mus musculus
PGFS-II
-
 Mus musculus

Cofactor

Cofactor Comment Organism Structure
NADPH
-
 Mus musculus