Inhibitors | Comment | Organism | Structure |
---|---|---|---|
acetone | pI 7.2 form | Gallus gallus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0022 | - |
NADPH | with 2,3-pentanedione | Gallus gallus | |
0.0024 | - |
NADPH | with glyoxal | Gallus gallus | |
0.0028 | - |
NADPH | with methylglyoxal | Gallus gallus | |
0.0031 | - |
NADPH | with diacetyl | Gallus gallus | |
0.035 | - |
2,3-Pentanedione | - |
Gallus gallus | |
0.09 | - |
methylglyoxal | pI 7.2 form | Gallus gallus | |
0.12 | - |
diacetyl | pI 7.2 form | Gallus gallus | |
0.41 | - |
Glyoxal | pI 7.2 form | Gallus gallus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Gallus gallus | - |
hen | - |
Purification (Comment) | Organism |
---|---|
- |
Gallus gallus |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
an L-glycol + NAD(P)+ = a 2-hydroxycarbonyl compound + NAD(P)H + H+ | glyoxal reduction by enzyme form pI 7.2 follows ordered bi-bi mechanism in which the coenzyme is the first substrate to bind to the enzyme | Gallus gallus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
muscle | - |
Gallus gallus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2,3-pentanedione + NADH | - |
Gallus gallus | L-acetylethylcarbinol + NAD+ | - |
? | |
diacetyl + NADH | - |
Gallus gallus | L-acetoin + NAD+ | - |
? | |
glyoxal + NADPH + H+ | - |
Gallus gallus | ? | - |
r | |
methylglyoxal + NADH | - |
Gallus gallus | L-lactaldehyde | - |
? | |
R1-CO-CO-R2 + NAD(P)H | methylglyoxal, diacetyl, 2,3-pentanedione | Gallus gallus | R1-CO-CHOH-R2 + NAD(P)+ | - |
? | |
R1-CO-CO-R2 + NAD(P)H | vicinal dicarbonyl: e.g. glyoxal | Gallus gallus | R1-CO-CHOH-R2 + NAD(P)+ | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADH | - |
Gallus gallus | |
NADPH | - |
Gallus gallus |