Literature summary for 1.1.1.184 extracted from

Gonzalez-Covarrubias, V.; Zhang, J.; Kalabus, J.L.; Relling, M.V.; Blanco, J.G.
Pharmacogenetics of human carbonyl reductase 1 (CBR1) in livers from black and white donors (2009), Drug Metab. Dispos., 37, 400-407.

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Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
cytosol	-	Homo sapiens	5829	-

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
30000	-	1 * 30000, immunoblot analysis	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P16152	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
liver	black and white donors, show similar CBR1 mRNA and protein levels. CBR1 1096G-A polymorphism is common in samples from white donors	Homo sapiens	-
lymphoblastoid cell line	GM10853, GM10845, GM10857, GM10858, GM10860, GM17240, GM16654, GM16688, and GM16689	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	CBR1 3'-untranslated region polymorphism 1096G-A in DNA samples from whites, and livers with homozygous G/G genotypes show a trend toward higher CBR1 mRNA levels compared with samples with heterozygous G/A genotypes. CBR1 1096G-A genotype status is associated with CBR1 protein levels	Homo sapiens	?	-	?

Subunits

Subunits	Comment	Organism
monomer	1 * 30000, immunoblot analysis	Homo sapiens

Synonyms

Synonyms	Comment	Organism
carbonyl reductase 1	-	Homo sapiens
CBR1	-	Homo sapiens

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Release 2023.1 (January 2023)