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Literature summary for 1.1.1.179 extracted from

  • Zepeda, S.; Monasterio, O.; Ureta, T.
    NADP(+)-dependent D-xylose dehydrogenase from pig liver. Purification and properties (1990), Biochem. J., 266, 637-644.
    View publication on PubMedView publication on EuropePMC

Inhibitors

Inhibitors Comment Organism Structure
L-Lyxose
-
Sus scrofa
NAD+
-
Sus scrofa

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.09
-
NADP+
-
Sus scrofa
6.5
-
D-xylose
-
Sus scrofa
8.8
-
D-xylose
-
Sus scrofa
27
-
D-ribose
-
Sus scrofa
49
-
D-glucose
-
Sus scrofa
54
-
2-deoxy-D-glucose
-
Sus scrofa
57
-
L-arabinose
-
Sus scrofa
130
-
D-arabinose
-
Sus scrofa
140
-
D-galactose
-
Sus scrofa

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
32000
-
2 * 32000, SDS-PAGE Sus scrofa
62000
-
gel filtration Sus scrofa

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Sus scrofa

Reaction

Reaction Comment Organism Reaction ID
D-xylose + NADP+ = D-xylono-1,5-lactone + NADPH + H+ mechanism Sus scrofa

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Sus scrofa
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [┬Ámol/min/mg] Specific Activity Maximum [┬Ámol/min/mg] Comment Organism
7.1
-
-
Sus scrofa

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-deoxy-D-glucose + NADP+
-
Sus scrofa 2-deoxy-D-glucono-1,5-lactone + NADPH + H+
-
?
D-arabinose + NADP+
-
Sus scrofa D-arabinono-1,5-lactone + NADPH + H+
-
r
D-galactose + NADP+
-
Sus scrofa D-galactono-1,5-lactone + NADPH
-
?
D-glucose + NADP+
-
Sus scrofa D-glucono-1,5-lactone + NADPH + H+
-
?
D-mannose + NADP+
-
Sus scrofa D-mannono-1,5-lactone + NADPH
-
?
D-ribose + NADP+
-
Sus scrofa ?
-
?
D-xylose + NADP+
-
Sus scrofa D-xylono-1,5-lactone + NADPH + H+
-
?
L-arabinose + NADP+
-
Sus scrofa L-arabinono-1,4-lactone + NADPH
-
?

Subunits

Subunits Comment Organism
dimer 2 * 32000, SDS-PAGE Sus scrofa

Temperature Optimum [┬░C]

Temperature Optimum [┬░C] Temperature Optimum Maximum [┬░C] Comment Organism
30
-
assay at Sus scrofa

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
9
-
D-arabinose
-
Sus scrofa
12
-
D-galactose
-
Sus scrofa
16
-
D-glucose
-
Sus scrofa
22
-
2-deoxy-D-glucose
-
Sus scrofa
40
-
D-ribose
-
Sus scrofa
45
-
L-arabinose
-
Sus scrofa
58
-
D-xylose
-
Sus scrofa

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8
-
-
Sus scrofa

Cofactor

Cofactor Comment Organism Structure
additional information not: NAD+ Sus scrofa
NADP+
-
Sus scrofa