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Literature summary for 1.1.1.17 extracted from

  • Velez, H.; Glassbrook, N.J.; Daub, M.E.
    Mannitol biosynthesis is required for plant pathogenicity by Alternaria alternata (2008), FEMS Microbiol. Lett., 285, 122-129.
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
additional information construction of a disruption mutant, that shows elevated levels of trehalose, but is viable, and the conidia germinate normally, the mutant is less pathogenic in infected tobacco plants compared to the wild-type fungus, overview Alternaria alternata

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
D-mannitol 1-phosphate + NAD+ Alternaria alternata the enzyme is involved in mannitol biosynthesis, which is required for plant pathogenicity by Alternaria alternata, overview D-fructose 6-phosphate + NADH + H+
-
r
D-mannitol 1-phosphate + NAD+ Alternaria alternata A5 the enzyme is involved in mannitol biosynthesis, which is required for plant pathogenicity by Alternaria alternata, overview D-fructose 6-phosphate + NADH + H+
-
r

Organism

Organism UniProt Comment Textmining
Alternaria alternata
-
-
-
Alternaria alternata A5
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
D-mannitol 1-phosphate + NAD+
-
Alternaria alternata D-fructose 6-phosphate + NADH + H+
-
r
D-mannitol 1-phosphate + NAD+ the enzyme is involved in mannitol biosynthesis, which is required for plant pathogenicity by Alternaria alternata, overview Alternaria alternata D-fructose 6-phosphate + NADH + H+
-
r
D-mannitol 1-phosphate + NAD+
-
Alternaria alternata A5 D-fructose 6-phosphate + NADH + H+
-
r
D-mannitol 1-phosphate + NAD+ the enzyme is involved in mannitol biosynthesis, which is required for plant pathogenicity by Alternaria alternata, overview Alternaria alternata A5 D-fructose 6-phosphate + NADH + H+
-
r

Synonyms

Synonyms Comment Organism
mannitol 1-phosphate 5-dehydrogenase
-
Alternaria alternata
MPDH
-
Alternaria alternata

Cofactor

Cofactor Comment Organism Structure
NAD+
-
Alternaria alternata
NADH
-
Alternaria alternata