Inhibitors | Comment | Organism | Structure |
---|---|---|---|
ketopantoyl lactone | - |
Saccharomyces cerevisiae | |
Polyketones | cyclohexenediol-1,2,3,4-tetraone; e.g. parabanic acid | Saccharomyces cerevisiae | |
quercetin | - |
Saccharomyces cerevisiae |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0031 | - |
5-bromoisatin | - |
Saccharomyces cerevisiae | |
0.0057 | - |
1-methylisatin | - |
Saccharomyces cerevisiae | |
0.0066 | - |
isatin | - |
Saccharomyces cerevisiae | |
0.0083 | - |
5-methylisatin | - |
Saccharomyces cerevisiae | |
0.0093 | - |
dihydro-5-isopropyl-4,4-dimethyl-2,3-furanedione | - |
Saccharomyces cerevisiae | |
0.0098 | - |
dihydro-5-(3-pentyl)-4,4-dimethyl-2,3-furanedione | - |
Saccharomyces cerevisiae | |
0.013 | - |
dihydro-5-(2-pentyl)-4,4-dimethyl-2,3-furanedione | - |
Saccharomyces cerevisiae | |
0.043 | - |
dihydro-5-(2-butyl)-4-methyl-4-ethyl-2,3-furanedione | - |
Saccharomyces cerevisiae | |
0.064 | - |
dl-camphorquinone | - |
Saccharomyces cerevisiae | |
0.09 | - |
dihydro-5-(2-pentyl)-4-methyl-4-propyl-2,3-furanedione | - |
Saccharomyces cerevisiae | |
0.093 | - |
beta-naphthoquinone | - |
Saccharomyces cerevisiae | |
0.17 | - |
ketopantoyl lactone | - |
Saccharomyces cerevisiae | |
0.42 | - |
dihydro-4,4-diethyl-2,3-furanedione | - |
Saccharomyces cerevisiae | |
0.52 | - |
ninhydrin | - |
Saccharomyces cerevisiae | |
0.83 | - |
alloxan | - |
Saccharomyces cerevisiae | |
0.983 | - |
dihydro-4-methyl-4-propyl-2,3-furanedione | - |
Saccharomyces cerevisiae |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-dehydropantoyl lactone + NADPH | Saccharomyces cerevisiae | - |
(R)-pantoyl lactone + NADP+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharomyces cerevisiae | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
1-methylisatin + NADPH | - |
Saccharomyces cerevisiae | ? | - |
? | |
2-dehydropantoyl lactone + NADPH | - |
Saccharomyces cerevisiae | (R)-pantoyl lactone + NADP+ | - |
? | |
5-bromoisatin + NADPH | - |
Saccharomyces cerevisiae | ? | - |
? | |
5-methylisatin + NADPH | - |
Saccharomyces cerevisiae | ? | - |
? | |
alloxan + NADPH | - |
Saccharomyces cerevisiae | ? | - |
? | |
beta-naphthoquinone + NADPH | - |
Saccharomyces cerevisiae | ? | - |
? | |
bornanedione + NADPH | - |
Saccharomyces cerevisiae | ? | - |
? | |
camphorquinone + NADPH | - |
Saccharomyces cerevisiae | ? | - |
? | |
dihydro-4,4-diethyl-2,3-furanedione + NADPH | - |
Saccharomyces cerevisiae | ? | - |
? | |
dihydro-4-methyl-4-propyl-2,3-furanedione + NADPH | - |
Saccharomyces cerevisiae | ? | - |
? | |
dihydro-5-(2-butyl)-4-methyl-4-ethyl-2,3-furanedione + NADPH | - |
Saccharomyces cerevisiae | ? | - |
? | |
dihydro-5-(2-pentyl)-4,4-dimethyl-2,3-furanedione + NADPH | - |
Saccharomyces cerevisiae | ? | - |
? | |
dihydro-5-(2-pentyl)-4-methyl-4-propyl-2,3-furanedione + NADPH | - |
Saccharomyces cerevisiae | ? | - |
? | |
dihydro-5-(3-pentyl)-4,4-dimethyl-2,3-furanedione + NADPH | - |
Saccharomyces cerevisiae | ? | - |
? | |
dihydro-5-isopropyl-4,4-dimethyl-2,3-furanedione + NADPH | - |
Saccharomyces cerevisiae | ? | - |
? | |
isatin + NADPH | and its derivatives | Saccharomyces cerevisiae | ? | - |
? | |
ketopantoyl lactone + NADPH | and its derivatives | Saccharomyces cerevisiae | D-(-)-pantoyl lactone | - |
? | |
ketopantoyl lactone + NADPH | - |
Saccharomyces cerevisiae | ? | - |
? | |
additional information | carbonyl reductase specifically catalyzing the reduction of conjugated polyketones | Saccharomyces cerevisiae | additional information | - |
? | |
naphthoquinone + NADPH | - |
Saccharomyces cerevisiae | ? | - |
? | |
ninhydrin + NADPH | - |
Saccharomyces cerevisiae | ? | - |
? |