Literature summary for 1.1.1.141 extracted from

Tariq, M.; Azeem, Z.; Ali, G.; Chishti, M.S.; Ahmad, W.
Mutation in the HPGD gene encoding NAD+ dependent 15-hydroxyprostaglandin dehydrogenase underlies isolated congenital nail clubbing (ICNC) (2009), J. Med. Genet., 46, 14-20.

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Protein Variants

Protein Variants	Comment	Organism
S193P	the missense mutation in exon 6 of the human HPGD gene encoding NAD+ dependent 15-hydroxyprostaglandin dehydrogenase is involved in the pathogenesis of isolated congenital nail clubbing	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
brain	-	Homo sapiens	-
skin	-	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
15-PGDH	-	Homo sapiens
NAD+ dependent 15-hydroxyprostaglandin dehydrogenase	-	Homo sapiens

Cofactor

Cofactor	Comment	Organism	Structure
NAD+	dependent on	Homo sapiens

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Release 2023.1 (January 2023)