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Literature summary for 1.1.1.14 extracted from
- Purification and properties of NAD-dependent sorbitol dehydrogenase from apple fruit (1994), Plant Cell Physiol., 35, 887-892.
No PubMed abstract available
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| CaCl2 | - |
Malus domestica |  |
| HgCl2 | - |
Malus domestica | |
| MgCl2 | - |
Malus domestica | |
| ZnCl2 | - |
Malus domestica | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 40.3 | - |
D-sorbitol | - |
Malus domestica | |
| 215 | - |
D-fructose | - |
Malus domestica | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 120000 | - |
gel filtration | Malus domestica |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Malus domestica | - |
apple | - |
| Malus domestica | - |
cv. Ourin | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| fruit | - |
Malus domestica | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 1.105 | - |
- |
Malus domestica |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| D-fructose + NADH + H+ | - |
Malus domestica | D-sorbitol + NAD+ | - |
? | |
| D-mannitol + NAD+ | - |
Malus domestica | ? | - |
? | |
| D-ribitol + NAD+ | - |
Malus domestica | ? | - |
? | |
| D-sorbitol + NAD+ | - |
Malus domestica | D-fructose + NADH + H+ | - |
? | |
| D-xylitol + NAD+ | - |
Malus domestica | ? | - |
? | |
| ethanol + NAD+ | - |
Malus domestica | acetaldehyde + NADH | - |
? | |
| L-arabitol + NAD+ | low activity | Malus domestica | ? | - |
? | |
| L-threitol + NAD+ | - |
Malus domestica | ? | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 6 | - |
D-fructose reduction | Malus domestica |
| 9.6 | - |
sorbitol oxidation | Malus domestica |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 5 | 7 | 30% of maximal activity at pH 5.0 and 60% of maximal activity at pH 7.0, fructose reduction | Malus domestica |
| 9 | 10.5 | less than 70% of maximal activity above and below, sorbitol oxidation | Malus domestica |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NAD+ | - |
Malus domestica | |
| NADH | - |
Malus domestica | |
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