Inhibitors | Comment | Organism | Structure |
---|---|---|---|
erythromycin | potent dose-dependent inhibitory effect, inhibition of biofilm formation, PT-1578 | Pseudomonas aeruginosa | |
midecamycin | weaker inhibition, no biofilm destruction, PT-1578 | Pseudomonas aeruginosa |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Pseudomonas aeruginosa | - |
mucoid clinical isolate PT-1578 and non-mucoid PAO1, very low activity of PAO1 regardless whether using nutrient-rich or poor medium, low activity with PT-1578 on enriched, increased on nutritionally poor medium | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
GDP-mannose + NAD+ + H2O | - |
Pseudomonas aeruginosa | GDP-mannuronate + NADH | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Pseudomonas aeruginosa |