Inhibitors | Comment | Organism | Structure |
---|---|---|---|
cellular retinol binding protein | free form without retinol | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0002 | - |
androsterone | pH 7.3, 37°C | Homo sapiens | |
0.00024 | - |
NAD+ | pH 7.3, 37°C | Homo sapiens | |
0.0027 | - |
retinol bound to cellular retinol binding protein | pH 7.3, 37°C | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | integral membrane protein facing cytosolic side of the membrane | Homo sapiens | - |
- |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
36000 | - |
x * 36000, SDS-PAGE | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
no glycoprotein | - |
Homo sapiens |
Purification (Comment) | Organism |
---|---|
solubilized enzyme is extremely unstable and loses almost 80% of the initial activity even at partially purified stage, purification uses resistance of enzyme to proteolysis at 4°C in the presence of 1% Triton | Homo sapiens |
Storage Stability | Organism |
---|---|
4°C, reconstitution of enzyme into proteoliposomes, stable for at least 4 months | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
androsterone + NAD+ | - |
Homo sapiens | ? + NADH | - |
? | |
additional information | substrate bound to cellular retinol binding protein is preferred | Homo sapiens | ? | - |
? | |
retinol + NAD+ | - |
Homo sapiens | retinal + NADH | - |
? | |
retinol bound to cellular retinol binding protein + NAD+ | - |
Homo sapiens | retinal bound to cellular retinol binding protein + NADH | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 36000, SDS-PAGE | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
RoDH-4 | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Homo sapiens |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00003 | - |
cellular retinol binding protein | pH 7.3, 37°C | Homo sapiens |