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Literature summary for 1.1.1.10 extracted from

  • Matsunaga, T.; Kamiya, T.; Sumi, D.; Kumagai, Y.; Kalyanaraman, B.; Hara, A.
    L-Xylulose reductase is involved in 9,10-phenanthrenequinone-induced apoptosis in human T lymphoma cells (2008), Free Radic. Biol. Med., 44, 1191-1202.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Homo sapiens
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Source Tissue

Source Tissue Comment Organism Textmining
MOLT-4 cell expression levels of L-xylulose reductase and its mRNA in the T lymphoma cells are markedly enhanced after the exposure to 9,10-phenanthrenequinone, and the induction is completely abolished by the ROS scavengers. L-Xylulose reductase is upregulated in the earlier step of the apoptosis and deteriorates the apoptotic signaling through the generation of ROS by the redox cycling of 9,10-phenanthrenequinone Homo sapiens
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Synonyms

Synonyms Comment Organism
L-xylulose reductase
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Homo sapiens