Ligand quinolin-4-ol

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Basic Ligand Information

Molecular Structure
Picture of quinolin-4-ol (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C9H7NO
quinolin-4-ol
PMZDQRJGMBOQBF-UHFFFAOYSA-N
Synonyms:
1H-4-Oxoquinoline, 4-hydroxyquinoline, 4-oxo-dihydroquinoline, 4-quinolinol

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
4-hydroxyquinoline + acceptor + H2O = ?
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
kynuramine + H2O + O2 = 4-hydroxyquinoline + NH3 + H2O2
show the reaction diagram
-
-

Inhibitor in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
Kd: 690 microM
IC50: 0.08 mM
-
binds at the polymerase active site interacting non-covalently with both the polymerase and the DNA duplex
-

3D Structure of Enzyme-Ligand-Complex (PDB) (1 result)

EC NUMBER
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

KM Value (1 result)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.025
-
-

IC50 Value (1 result)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE
0.08
-
IC50: 0.08 mM

References & Links

Links to other databases for quinolin-4-ol

ChEBI
PubChem
ChEBI
PubChem