Ligand gibberellin A4

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Basic Ligand Information

Molecular Structure
Picture of gibberellin A4 (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C19H24O5
gibberellin A4
RSQSQJNRHICNNH-NFMPGMCNSA-N
Synonyms:
2beta-hydroxygibberellin 4, gibberellin 4, giberellic acid GA4, [1,2-3H2]gibberellin 4

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
giberellic acid GA4 + [reduced NADPH-hemoprotein reductase] + O2 = 16alpha,17-epoxy GA4 + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
-
S-adenosyl-L-methionine + gibberellin A4 = S-adenosyl-L-homocysteine + methyl gibberellin A4
show the reaction diagram
-

In Vivo Product in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Substrate in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
giberellic acid GA4 + [reduced NADPH-hemoprotein reductase] + O2 = 16alpha,17-epoxy GA4 + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
-
S-adenosyl-L-methionine + gibberellin A4 = S-adenosyl-L-homocysteine + methyl gibberellin A4
show the reaction diagram
-
S-adenosyl-L-methionine + gibberellin A4 = S-adenosyl-L-homocysteine + methyl gibberellin A4
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
gibberellin 4 + 2-oxoglutarate + O2 = 2beta-hydroxygibberellin 4 + succinate + CO2
show the reaction diagram
-
-

Inhibitor in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
50% inhibition at 0.2-0.3 nmol
-
treatment causes down-regulation of gibberellin-insensitive dwarf 1, gibberellin A20 oxidase, and gibberellin 3beta-dioxygenase as well as degradation of DELLA1 protein
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (2 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
0.01
-
pH 8.0, 30°C
0.0015
-
pH 8.0, 30°C

KM Value (4 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.0054
-
pH 8.0, 30°C
0.0059
-
pH 8.0, 30°C

References & Links

Links to other databases for gibberellin A4

ChEBI
PubChem
ChEBI
PubChem