Ligand maleamic acid

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Basic Ligand Information

Molecular Structure
Picture of maleamic acid (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C4H5NO3
maleamic acid
FSQQTNAZHBEJLS-UPHRSURJSA-N
Synonyms:
(2Z)-4-amino-4-oxobut-2-enoic acid, Maleamate, maleic acid monoamide

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
maleamate + H2O = maleate + NH3
show the reaction diagram
-

In Vivo Product in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2,5-dihydroxypyridine + O2 + H2O = maleamate + formate
show the reaction diagram
-
-
N-formylmaleamic acid + H2O = maleamate + formate
show the reaction diagram
-
-

Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
maleamate + H2O = maleate + NH3
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2,5-dihydroxypyridine + O2 + H2O = maleamate + formate
show the reaction diagram
-
-
N-formylmaleamic acid + H2O = maleamate + formate
show the reaction diagram
-
-
maleimide + H2O = maleic acid monoamide
show the reaction diagram
-

Inhibitor in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
reversible, competitive
-

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (1 result)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
11.7
-
pH 7.5, 25°C

KM Value (1 result)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.128
-
pH 7.5, 25°C

Ki Value (1 result)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
11.6
-
30°C, pH 7.0

References & Links

Links to other databases for maleamic acid

ChEBI
PubChem
ChEBI
PubChem