Ligand CDTA

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Basic Ligand Information

Molecular Structure
Picture of CDTA (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C14H22N2O8
CDTA
UFTNTRBFUIZYLZ-OOJLDXBWSA-N
Synonyms:
trans-1,2-cyclohexandiaminetetraacetic acid, trans-1,2-diaminocyclohexane-N',N',N',N'-tetraacetic acid

Roles as Enzyme Ligand

Activator in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE

Inhibitor in Enzyme-catalyzed Reactions (10 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
0.08% residual activity at 2.5 mM
-
strong inhibition
-
strong inhibition
-
10 mM, 10% inhibition
-
complete inhibition at 1-10 mM
-
about 90% inhibition; enzyme results in about 90% loss of activity, when dialyzed overnight against the metal chelator. Some restoration of activity is observed with all of the metal salts (10 mM ZnCl2, MgCl2, CaCl2, CoCl2, or NiCl). The addition of ZnCl2, MgCl2, and CaCl2 is the most effective, restoring 70-80% of the activity, with NiCl2 restoring about 50% and CoCl2 the least effective at only about 25%
-
inhibition 42%
-

Enzyme Kinetic Parameters

References & Links

Links to other databases for CDTA

ChEBI
PubChem
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PubChem