Ligand thiamine diphosphate

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

Basic Ligand Information

Molecular Structure
Picture of thiamine diphosphate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C12H18N4O7P2S
thiamine diphosphate
AYEKOFBPNLCAJY-UHFFFAOYSA-O
Synonyms:
thiamin diphosphate, thiamindiphosphate, ThPP, TPP


Show all pahtways known for Show all BRENDA pathways known for thiamine diphosphate

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
thiamine diphosphate + H2O = thiamine phosphate + phosphate
show the reaction diagram
-
thiamine diphosphate + 2 H2O = thiamine + 2 phosphate
show the reaction diagram
-
thiamine diphosphate + H2O = ?
show the reaction diagram
-

In Vivo Product in Enzyme-catalyzed Reactions (8 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
thiamine triphosphate + H2O = thiamine diphosphate + phosphate
show the reaction diagram

Substrate in Enzyme-catalyzed Reactions (13 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
thiamin diphosphate + H2O = thiamin phosphate + phosphate
show the reaction diagram
-
thiamine diphosphate + H2O = thiamine phosphate + phosphate
show the reaction diagram
-
thiamine diphosphate + H2O = ?
show the reaction diagram
-
thiamine diphosphate + H2O = thiamine monophosphate + phosphate
show the reaction diagram
thiamine diphosphate + 2 H2O = thiamine + 2 phosphate
show the reaction diagram
-
TPP + H2O = thiamine phosphate + phosphate
show the reaction diagram
-
thiamine diphosphate + H2O = ?
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (12 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Enzyme Cofactor/Cosubstrate (2422 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
reaction is strictly dependent on
-
optimal activity at 0.004 mM, absolute requirement
-
1.6 mol per mol of enzyme
-