Ligand dCDP

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Basic Ligand Information

Molecular Structure
Picture of dCDP (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C9H15N3O10P2
dCDP
FTDHDKPUHBLBTL-SHYZEUOFSA-N
Synonyms:
(d)CDP, 2'-dCDP, 2'-deoxycytidine 5'-diphosphate, D-dCDP, deoxy-5'-CDP


Show all pahtways known for Show all BRENDA pathways known for dCDP

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
dCDP + (phosphate)n+1 = dCTP + (phosphate)n
show the reaction diagram
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dCDP + H2O = dCMP + phosphate
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
CDP + thioredoxin = 2'-dCDP + thioredoxin disulfide + H2O
show the reaction diagram
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ATP + dCMP = ADP + dCDP
show the reaction diagram
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ATP + dCMP = ADP + dCDP
show the reaction diagram
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ATP + dCMP = ADP + dCDP
show the reaction diagram
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dCTP + H2O = dCDP + phosphate
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (14 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
dCDP + DTT disulfide + H2O = CDP + DTT
show the reaction diagram
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dCDP + phosphoenolpyruvate = dCTP + pyruvate
show the reaction diagram
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dCDP + phosphoramide = dCTP + NH3
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dCDP + (phosphate)n+1 = dCTP + (phosphate)n
show the reaction diagram
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dCDP + H2O = ?
show the reaction diagram
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dCDP + H2O = dCMP + phosphate
show the reaction diagram
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dCDP + H2O = dCMP + phosphate
show the reaction diagram
-
dCDP + H2O = ?
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (54 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
dCTP + dolichol = dCDP + dolichyl phosphate
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dCTP + deoxyguanosine = dCDP + dGMP
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dCTP + D-ribose = dCDP + D-ribose 5-phosphate
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dCTP + 1,2-diacyl-sn-glycerol = dCDP + 1,2-diacyl-sn-glycerol 3-phosphate
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dCTP + NAD+ = dCDP + NADP+
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pantothenate + dCTP = 4'-phosphopantothenate + dCDP
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dCTP + mevalonate = dCDP + phosphomevalonate
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dCTP + 4-methyl-5-(2-hydroxyethyl)thiazole = dCDP + 4-methyl-5-(2-phosphonooxyethyl)thiazole
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dCTP + D-galactose = dCDP + alpha-D-galactose 1-phosphate
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dCTP + deoxyadenosine = dCDP + dAMP
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2'-deoxycytidine 5'-triphosphate + 3-phospho-D-glycerate = 2'-deoxycytidine 5'-diphosphate + 1,3-diphosphoglycerate
show the reaction diagram
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ATP + dCMP = ADP + dCDP
show the reaction diagram
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dCTP + 5-methyldeoxycytidine 5'-phosphate = dCDP + 5-methyldeoxycytidine diphosphate
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dCTP + UMP = dCDP + UDP
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dCMP + [phosphate]n = dCDP + [phosphate]n-1
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dCTP + H2O = dCDP + phosphate
show the reaction diagram
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dCTP + H2O = dCDP + phosphate
show the reaction diagram
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glucose + dCTP = glucose 6-phosphate + dCDP
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dCTP + H2O = dCDP + phosphate
show the reaction diagram
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dCTP + H2O = dCDP + phosphate
show the reaction diagram
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dCTP + H2O = dCDP + phosphate
show the reaction diagram
-
dCTP + H2O = dCDP + phosphate
show the reaction diagram
-
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dCTP + H2O = dCDP + phosphate
show the reaction diagram
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dCTP + H2O = dCDP + phosphate
show the reaction diagram
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dCTP + H2O + closed Cl- channel = dCDP + phosphate + open Cl- channel
show the reaction diagram
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Activator in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
slight stimulation, with ATP as substrate
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slightly stimulates synthesis of guanosine 3'-diphosphate 5'-triphosphate, inhibits polynucleotide phosphorylase activities of enzyme
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Inhibitor in Enzyme-catalyzed Reactions (10 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
product inhibition
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0.001 mM, 60% inhibition
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competitive inhibition of hydrolysis of dCTP
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3D Structure of Enzyme-Ligand-Complex (PDB) (5 results)

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (4 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
1.12
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substrate concentration between 0.01 and 4.0 mM, 37°C

KM Value (8 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.092
-
substrate concentration between 0.01 and 4.0 mM, 37°C

References & Links

Links to other databases for dCDP

ChEBI
PubChem
ChEBI
PubChem