Ligand 2-methylacetoacetyl-CoA

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Basic Ligand Information

Molecular Structure
Picture of 2-methylacetoacetyl-CoA (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C26H42N7O18P3S
2-methylacetoacetyl-CoA
NHNODHRSCRALBF-XPQQUFCKSA-N
Synonyms:
2-methyl-acetoacetyl-CoA

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2-methylacetoacetyl-CoA + CoA = acetyl-CoA + propionyl-CoA
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2-methyl-3-hydroxybutyryl-CoA + NAD+ = 2-methylacetoacetyl-CoA + NADH
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2-methylacetoacetyl-CoA + NADPH = 2-methyl-3-hydroxybutyryl-CoA + NADP+
show the reaction diagram
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2-methylacetoacetyl-CoA + CoA = acetyl-CoA + propionyl-CoA
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
butanoyl-CoA + 2-methylacetoacetate = butanoate + 2-methylacetoacetyl-CoA
show the reaction diagram
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3D Structure of Enzyme-Ligand-Complex (PDB) (1 result)

EC NUMBER
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (1 result)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
27
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KM Value (1 result)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.74
-
-

References & Links

Links to other databases for 2-methylacetoacetyl-CoA

ChEBI
PubChem
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PubChem