Ligand 2,6-Dihydroxypyridine

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Basic Ligand Information

Molecular Structure
Picture of 2,6-Dihydroxypyridine (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C5H5NO2
2,6-Dihydroxypyridine
WLFXSECCHULRRO-UHFFFAOYSA-N
Synonyms:
6-hydroxy-1H-pyridin-2-one

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2,6-dihydroxypyridine + NADH + O2 = 2,3,6-trihydroxypyridine + NAD+ + H2O
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2,6-dihydroxypyridine + O2 = ? + H2O2
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2,6-dihydroxypseudooxynicotine + H2O = 2,6-dihydroxypyridine + 4-methylaminobutanoate
show the reaction diagram
-
-

Inhibitor in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
competitive vs. uracil
-
38% inhibition at 0.001 mM
-

Enzyme Kinetic Parameters

KM Value (1 result)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.0083
-
pH 8, 20°C

References & Links

Links to other databases for 2,6-Dihydroxypyridine

ChEBI
PubChem
ChEBI
PubChem