Ligand 2,3-dichloro-1,4-naphthoquinone

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Basic Ligand Information

Molecular Structure
Picture of 2,3-dichloro-1,4-naphthoquinone (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C10H4ClO2
2,3-dichloro-1,4-naphthoquinone
SVPKNMBRVBMTLB-UHFFFAOYSA-N
Synonyms:
2,3-dichloronaphthalene-1,4-dione, 2,3-dichloronaphthoquinone

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
D-glucose + 2,3-dichloro-1,4-naphthoquinone = D-glucono-1,5-lactone + ?
show the reaction diagram
-
2,3-dichloro-1,4-naphthoquinone + NADP+ = ? + NADPH + H+
show the reaction diagram
-
2,3-dichloro-1,4-naphthoquinone + NADPH + H+ = 2,3-dichloro-1,4-naphthoquinol + NADP+
show the reaction diagram
-

Enzyme Cofactor/Cosubstrate (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
in the mutant menB deletion strain
-

Inhibitor in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
IC50: 0.26 mM
-

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (1 result)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
61
-
pH 7.0, 25°C

KM Value (1 result)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.022
-
pH 7.0, 25°C

IC50 Value (3 results)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE
0.00028
-
-
0.011
-
pH 7.5, 30°C
0.26
-
IC50: 0.26 mM

References & Links

Links to other databases for 2,3-dichloro-1,4-naphthoquinone

ChEBI
PubChem
-
PubChem