Ligand erythromycin D

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Basic Ligand Information

Molecular Structure
Picture of erythromycin D (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C36H65NO12
erythromycin D
CLQUUOKNEOQBSW-KEGKUKQHSA-N

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
erythromycin D + NADPH + H+ + O2 = erythromycin C + NADP+ + H2O
show the reaction diagram
S-adenosyl-L-methionine + erythromycin D = S-adenosyl-L-homocysteine + erythromycin B
show the reaction diagram
-

In Vivo Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
dTDP-3-dimethylamino-4,6-dideoxy-alpha-D-glucopyranose + 3-alpha-mycarosylerythronolide B = dTDP + erythromycin D
show the reaction diagram
-
-

Substrate in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
erythromycin D + NADPH + H+ + O2 = erythromycin C + NADP+ + H2O
show the reaction diagram
S-adenosyl-L-methionine + erythromycin D = S-adenosyl-L-homocysteine + erythromycin B
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Inhibitor in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
substrate inhibition

3D Structure of Enzyme-Ligand-Complex (PDB) (1 result)

EC NUMBER
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (1 result)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
1.8
-
pH 7.5, 30°C

KM Value (1 result)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.008
-
pH 7.5, 30°C

Ki Value (1 result)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
TABLE ID
0.0166
-
pH 7.5, 30°C
7400

References & Links

Links to other databases for erythromycin D

ChEBI
PubChem
ChEBI
PubChem