Ligand 1-palmitoyl-sn-glycero-3-phosphocholine

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Basic Ligand Information

Molecular Structure
Picture of 1-palmitoyl-sn-glycero-3-phosphocholine (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C24H50NO7P
1-palmitoyl-sn-glycero-3-phosphocholine
ASWBNKHCZGQVJV-HSZRJFAPSA-O
Synonyms:
1-hexadecanoyl-glycero-3-phosphocholine, 1-hexadecanoyl-sn-glycero-3-phosphocholine, 1-monopalmitoyllysophosphatidylcholine, 1-O-Hexadecanoyl-sn-glycerol-3-phosphocholine, 1-palmitoyl-2-lyso-glycerophoshorylcholine, 1-palmitoyl-2-lyso-glycerophosphocholine, 1-palmitoyl-2-lyso-sn-glycero-3-phosphocholine, 1-palmitoyl-2-lyso-sn-phosphatidylcholine, 1-palmitoyl-2-lysophosphatidylcholine, 1-palmitoyl-glycerophoshorylcholine, 1-palmitoyl-glycerophosphocholine, 1-palmitoyl-glycerophosphorylcholine, 1-palmitoyl-lysophosphatidylcholine, 1-palmitoyl-sn-glycero-3-phosphatidylcholine, 1-Palmitoyl-sn-glycero-3-phosphorylcholine, 1-palmitoyl-sn-glycerol-3-phosphocholine, 1-palmitoyl-sn-glycerol-3-phosphorylcholine, 1-palmitoyl-sn-glycerophosphocholine, 1-palmitoyl-sn-glycerophosphorylcholine, 1-palmitoyl-sn-lysophosphatidylcholine, 1-palmitoylglycerophosphocholine, 1-Palmitoylglycerophosphorylcholine, 1-palmitoyl lysophosphatidylcholine, 1-palmitoyllysophosphatidylcholine, 1-palmitoyl phosphatidylcholine, 16:0 lysophosphatidylcholine, lysophosphatidylcholine 16:0, monopalmitoyl-lysophosphatidylcholine, Palmitoyl-2-lyso-sn-glycero-3-phosphocholine, palmitoyl-lysophosphatidylcholine, palmitoyllyso-glycero-3-phosphocholine, sn-1-palmitoyl-lysophosphatidylcholine

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (7 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
1-palmitoyl-sn-glycero-3-phosphocholine + H2O = ?
show the reaction diagram
-

In Vivo Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
1,2-dipalmitoyl-sn-glycero-3-phosphocholine + H2O = 1-palmitoylglycerophosphocholine + palmitic acid
show the reaction diagram
-
-

Substrate in Enzyme-catalyzed Reactions (62 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
1-palmitoyl-sn-glycerol-3-phosphorylcholine + retinol = retinyl palmitate + glycerol-3-phosphorylcholine
show the reaction diagram
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1-hexadecanoyl-sn-glycero-3-phosphocholine + 1-organyl-2-lyso-sn-glycero-3-phospholipid = 1-organyl-sn-glycero-3-phosphocholine + 1-O-hexadecanoyl-2-lyso-sn-glycero-3-phospholipid
show the reaction diagram
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acetyl-CoA + 1-palmitoyl-2-lyso-sn-glycero-3-phosphocholine = CoA + 2-acetyl-1-palmitoyl-sn-glycero-3-phosphocholine
show the reaction diagram
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1-palmitoyl-2-lysophosphatidylcholine + H2O = palmitic acid + glycerophosphorylcholine
show the reaction diagram
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1-palmitoyllysophosphatidylcholine + H2O = palmitic acid + lysophosphatidylcholine
show the reaction diagram
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1-palmitoyl lysophosphatidylcholine + H2O = glycerophosphocholine + palmitate
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (54 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
palmitoyl-CoA + glycerophosphocholine = CoA + 1-palmitoyl-sn-glycero-3-phosphocholine
show the reaction diagram
-
-
1,2-dipalmitoyl-sn-glycero-3-phosphocholine + H2O = 1-palmitoyl-sn-glycero-3-phosphocholine + palmitate
show the reaction diagram
-
1-palmitoyl-2-arachidonyl-sn-glycero-3-phosphocholine + H2O = arachidonic acid + 1-palmitoyl-sn-glycero-3-phosphocholine
show the reaction diagram
-
-

Inhibitor in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
competitive inhibitor for acylprotein thioesterase activity
-
competitive inhibitor for acylprotein thioesterase activity
-

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (1 result)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
921.1
-
at pH 8.0 and 37C

KM Value (20 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.017
-
-
0.0273
-
-

Ki Value (2 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.0222
-
for acylprotein thioesterase activity
0.0222
-
for acylprotein thioesterase activity

References & Links

Links to other databases for 1-palmitoyl-sn-glycero-3-phosphocholine

ChEBI
PubChem
ChEBI
PubChem