Ligand testololactone

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Basic Ligand Information

Molecular Structure
Picture of testololactone (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C19H26O3
testololactone
CNIXJDVUMXTEKX-DZBHQSCQSA-N
Synonyms:
3-oxo-13,17-secoandrost-4-ene-17,13alpha-lactone, 3-oxo-13,17-secoandrost-4-eno-17,13-alpha-lactone, 17alpha-oxa-D-homo-androst-4-ene-3,17-dione
Pathway Source
Pathways

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
testololactone + H2O = ?
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
androst-4-ene-3,17-dione + AH2 + O2 = 3-oxo-13,17-secoandrost-4-ene-17,13alpha-lactone + A + H2O
show the reaction diagram
-
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Substrate in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
testololactone + acceptor = D-homo-17alpha-oxoandrosta-1,4-diene-3,17-one + reduced acceptor
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
androstenedione + NADPH + O2 = 3-oxo-13,17-secoandrost-4-eno-17,13-alpha-lactone + NADP+ + H2O
show the reaction diagram
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testolate = testololactone + H2O
show the reaction diagram
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (1 result)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
0.45
-
formed

KM Value (1 result)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.0143
-
i.e. 17alpha-oxo-D-homo-1,4-androstadiene-3,17-dione

References & Links

Links to other databases for testololactone

ChEBI
PubChem
ChEBI
PubChem