Ligand 5'-phosphomononucleotides

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Basic Ligand Information

Molecular Structure
Picture of 5'-phosphomononucleotides (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C5H10O7PR
5'-phosphomononucleotides
SPZDHSUJIZCYOY-TXICZTDVSA-N
Synonyms:
5'-phosphomononucleotide, 5'-phosphoribonucleoside, 5-nucleotide, A 5'-ribonucleotide, a nucleoside 5'-phosphate, A nucleotide, mononucleotide, Mononucleotides, NMP, nucleoside 5'-monophosphate, nucleoside 5'-monophosphates, nucleoside 5'-phosphate, nucleoside 5'-phosphates, nucleoside 5'monophosphate, nucleoside monophosphate, nucleoside monophosphates, nucleoside phosphate, nucleoside phosphates, Nucleotide, ribonucleoside 5'-phosphate
Pathway Source
Pathways
MetaCyc

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
a nucleotide + H2O = a nucleoside + phosphate
show the reaction diagram
-
a 5'-ribonucleotide + H2O = a ribonucleoside + phosphate
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (18 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
single-stranded DNA + H2O = 5'-phosphomononucleotides
show the reaction diagram
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oligonucleotides + H2O = nucleoside 5'-phosphates
show the reaction diagram
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RNA + H2O = 5'-phosphomononucleotides
show the reaction diagram
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RNA + H2O = nucleoside 5'-monophosphates
show the reaction diagram
-
RNA-DNA*DNA hybrid + H2O = DNA*DNA + 5'-phosphomononucleotides
show the reaction diagram
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nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate
show the reaction diagram
-
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p-nitrophenyl 5'-nucleotides + H2O = p-nitrophenol + nucleoside phosphate
show the reaction diagram
-
polynucleotide + H2O = nucleoside 5'-phosphate + ?
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
S-adenosyl-L-methionine + mononucleotide = ?
show the reaction diagram
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a nucleotide + H2O = a nucleoside + phosphate
show the reaction diagram
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a 5'-ribonucleotide + H2O = a ribonucleoside + phosphate
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (46 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
NDP + arsenate = NMP + phosphate + ?
show the reaction diagram
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dinucleotide monophosphates + H2O = nucleoside + nucleoside 5'-monophosphate
show the reaction diagram
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RNA-DNA*DNA hybrid + H2O = DNA*DNA + 5'-phosphomononucleotides
show the reaction diagram
-
-
nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate
show the reaction diagram
-
NDP + H2O = NMP + phosphate
show the reaction diagram
-
-
p-nitrophenyl 5'-nucleotides + H2O = p-nitrophenol + nucleoside phosphate
show the reaction diagram
-
NDP + H2O = NMP + phosphate
show the reaction diagram
-
-
nucleoside diphosphate + H2O = nucleoside phosphate + phosphate
show the reaction diagram
-
-
polynucleotide + H2O = nucleoside 5'-phosphate + ?
show the reaction diagram
-
RNA + H2O = 5'-phosphomononucleotides
show the reaction diagram
-

Activator in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE

Inhibitor in Enzyme-catalyzed Reactions (9 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
overview
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degree of inhibition in decreasing order: nucleoside-triphosphate, nucleoside-diphosphate, nucleoside-monophosphate
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e.g. 2'-GMP, 3'-GMP, 5'-GMP, 3'-CMP, 2'(3')-UMP
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with 5'-phosphate end group
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slight inhibition or no effect
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (4 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
3.33
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References & Links

Links to other databases for 5'-phosphomononucleotides

ChEBI
PubChem
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PubChem