Ligand (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA

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Basic Ligand Information

Molecular Structure
Picture of (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C48H80N7O20P3S
(25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA
MNYDLIUNNOCPHG-FJWDCHQMSA-N
Synonyms:
(25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA, (25R)-trihydroxycoprostanoyl-CoA, (R)-trihydroxycoprostanoyl-CoA, 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA, trihydroxycoprostanoyl-CoA


Show all pahtways known for Show all BRENDA pathways known for (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
trihydroxycoprostanoyl-CoA + H2O = trihydroxycoprostanate + CoA
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
ATP + 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanate + CoA = AMP + diphosphate + 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (7 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
trihydroxycoprostanoyl-CoA + H2O + acceptor = 3alpha,7alpha,12alpha,24-tetrahydroxycoprostanoyl-CoA + reduced acceptor
show the reaction diagram
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trihydroxycoprostanoyl-CoA + O2 = ?
show the reaction diagram
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trihydroxycoprostanoyl-CoA + H2O = CoA + trihydroxycoprostanoate
show the reaction diagram
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trihydroxycoprostanoyl-CoA + H2O = CoA + trihydroxycoprostanoate
show the reaction diagram
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trihydroxycoprostanoyl-CoA + H2O = trihydroxycoprostanate + CoA
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
ATP + 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanate + CoA = AMP + diphosphate + 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA
show the reaction diagram
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Inhibitor in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

KM Value (3 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.0063
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pH 7.4

References & Links

Links to other databases for (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA

ChEBI
PubChem
ChEBI
PubChem