Ligand (4S)-4,6-dihydroxy-2,5-dioxohexanoate

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Basic Ligand Information

Molecular Structure
Picture of (4S)-4,6-dihydroxy-2,5-dioxohexanoate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C6H8O6
(4S)-4,6-dihydroxy-2,5-dioxohexanoate
IBGYNIRCYXIAON-VKHMYHEASA-N
Synonyms:
(4S)-2,5-dioxo-4,6-dihydroxyhexanoate, (4S)-4,6-dihydroxy-2,5-dioxohexanoic acid, 2,5-didehydro-3-deoxy-D-gluconate, 2,5-didehydro-3-deoxy-L-galactonate, 2,5-diketo-3-deoxygluconate, 3-deoxy-D-glycero-2,5-hexodiulosonate

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

In Vivo Product in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2-dehydro-3-deoxy-D-gluconate + NAD+ = (4S)-4,6-dihydroxy-2,5-dioxohexanoate + NADH
show the reaction diagram
-
2-dehydro-3-deoxy-L-galactonate + NAD+ = 2,5-didehydro-3-deoxy-L-galactonate + NADH + H+
show the reaction diagram
-
-
5-dehydro-4-deoxy-D-glucuronate = (4S)-4,6-dihydroxy-2,5-dioxohexanoate
show the reaction diagram
-
-

Substrate in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Product in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2-dehydro-3-deoxy-D-gluconate + NAD+ = (4S)-4,6-dihydroxy-2,5-dioxohexanoate + NADH
show the reaction diagram
-
2-dehydro-3-deoxy-L-galactonate + NAD+ = 2,5-didehydro-3-deoxy-L-galactonate + NADH + H+
show the reaction diagram
-
-

Enzyme Kinetic Parameters

KM Value (1 result)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.34
-
-

References & Links

Links to other databases for (4S)-4,6-dihydroxy-2,5-dioxohexanoate

ChEBI
PubChem
ChEBI
PubChem