Ligand nicotinic acid mononucleotide

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Basic Ligand Information

Molecular Structure
Picture of nicotinic acid mononucleotide (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C11H14NO9P
nicotinic acid mononucleotide
JOUIQRNQJGXQDC-ZYUZMQFOSA-O
Synonyms:
beta-nicotinate D-ribonucleotide, deamido-NMN, deamino-NMN, nicotinate beta-D-ribonucleotide, nicotinate D-ribonucleotide, nicotinate mononucleotide, nicotinate nucleotide, nicotinate ribonucleotide, nicotinic acid ribonucleotide


Show all pahtways known for Show all BRENDA pathways known for nicotinic acid mononucleotide

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (30 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

In Vivo Product in Enzyme-catalyzed Reactions (16 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
ATP + beta-D-ribosylnicotinate = ADP + nicotinate beta-D-ribonucleotide
show the reaction diagram
-
-
nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate
show the reaction diagram
-

Substrate in Enzyme-catalyzed Reactions (187 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
nicotinic acid mononucleotide + H2O = nicotinic acid + ribose 5-phosphate
show the reaction diagram
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ATP + deamido-NMN + NH3 = AMP + diphosphate + NMN
show the reaction diagram
-
ATP + deamido-NMN + L-Gln = AMP + diphosphate + NMN + L-Glu
show the reaction diagram
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DMB + nicotinic acid mononucleotide = DMB-ribose-5'-phosphate
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (23 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
deamino-NAD+ + H2O = deamino-NMN + AMP
show the reaction diagram
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-
nicotinic acid adenine dinucleotide + H2O = nicotinic acid mononucleotide + 5'-AMP
show the reaction diagram
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nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate
show the reaction diagram

Inhibitor in Enzyme-catalyzed Reactions (18 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
nicotinamide ribonucleotide as substrate
-

3D Structure of Enzyme-Ligand-Complex (PDB) (14 results)

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (21 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
0.5
-
-
0.0032
-
pH 7.5, 30°C

KM Value (44 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.2
-
-
4.3
-
pH 7.5, 30°C

Ki Value (2 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

References & Links

Links to other databases for nicotinic acid mononucleotide

ChEBI
PubChem
ChEBI
PubChem