Ligand (-)-menthone

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Basic Ligand Information

Molecular Structure
Picture of (-)-menthone (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C10H18O
(-)-menthone
NFLGAXVYCFJBMK-BDAKNGLRSA-N
Synonyms:
(1R)-menthone, (1R)-trans-p-menthan-3-one, (1R,4S)-menthone, (2S,5R)-5-methyl-2-(propan-2-yl)cyclohexan-1-one, (2S,5R)-menthone

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (7 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(2S,5R)-5-methyl-2-(propan-2-yl)cyclohexan-1-one + NADP+ = (2S,5R)-5-methyl-2-(propan-2-yl)cyclohexan-1-ol + (1S,2R,5R)-5-methyl-2-(propan-2-yl)cyclohexan-1-ol + NADPH + H+
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Substrate in Enzyme-catalyzed Reactions (11 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(1R,4S)-menthone + NADPH + H+ + O2 = (4R,7S)-7-isopropyl-4-methyl-2-oxo-oxepanone + NADP+ + H2O
show the reaction diagram
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(2S,5R)-5-methyl-2-(propan-2-yl)cyclohexan-1-one + NADP+ = (2S,5R)-5-methyl-2-(propan-2-yl)cyclohexan-1-ol + (1S,2R,5R)-5-methyl-2-(propan-2-yl)cyclohexan-1-ol + NADPH + H+
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(1R)-menthol + NAD+ = (1R)-trans-p-menthan-3-one + NADH
show the reaction diagram
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(+)-neomenthol + NADP+ = (-)-menthone + NADPH + H+
show the reaction diagram
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(R)-pulegone + NADP+ = (1R,4R)-isomenthone + (1R,4S)-menthone + NADPH + H+
show the reaction diagram
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(R)-pulegone + NADPH + H+ = (1R,4R)-isomenthone + (1R,4S)-menthone + NADP+
show the reaction diagram
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (6 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
3.6
-
30°C and glyine/NaOH buffer, pH 9.5

KM Value (5 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.12
-
30°C and glyine/NaOH buffer, pH 9.5

References & Links

Links to other databases for (-)-menthone

ChEBI
PubChem
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PubChem