Ligand 2-hydroxypyrimidine

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Basic Ligand Information

Molecular Structure
Picture of 2-hydroxypyrimidine (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C4H4N2O
2-hydroxypyrimidine
VTGOHKSTWXHQJK-UHFFFAOYSA-N
Synonyms:
2-pyrimidinol, 2-pyrimidinone, 2-pyrimidone, a pyrimidine base, pyrimidin-2-one

Roles as Enzyme Ligand

In Vivo Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
a pyrimidine nucleoside + H2O = D-ribose + a pyrimidine base
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (12 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
thymidine + 2-pyrimidinol = thymine + ?
show the reaction diagram
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pyrimidin-2-one + H2O = (4R)-hydroxyl-3,4-dihydropyrimidine + ?
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
a pyrimidine nucleoside + H2O = D-ribose + a pyrimidine base
show the reaction diagram
-
-

Inhibitor in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
forms a part of inhibitor 1,2-dihydropyrimidin-2-one-5-methylene-(methylsulfonium)-adenosyl, bindng structure and mechanism, overview
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (2 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE

KM Value (8 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

References & Links

Links to other databases for 2-hydroxypyrimidine

ChEBI
PubChem
ChEBI
PubChem