Ligand glycerol 2-phosphate

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Basic Ligand Information

Molecular Structure
Picture of glycerol 2-phosphate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C3H9O6P
glycerol 2-phosphate
DHCLVCXQIBBOPH-UHFFFAOYSA-N
Synonyms:
2-glycerol phosphate, 2-glycerophosphate, 2-Phosphoglycerol, beta-glycerol phosphate, beta-Glycerophosphate, beta-Glycerophosphate buffer, glycerol-2-phosphate
Pathway Source
Pathways

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
glycerol 2-phosphate + H2O = glycerol + phosphate
show the reaction diagram
-
glycerol 2-phosphate + H2O = glycerol + phosphate
show the reaction diagram
-

Substrate in Enzyme-catalyzed Reactions (38 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
beta-glycerophosphate + NAD+ = ?
show the reaction diagram
-
beta-glycerophosphate + uridine = glycerol + UMP
show the reaction diagram
-
adenosine 5'-triphosphate + glycerol-2-phosphate = adenosine 5'-monophosphate-O-glyceryl-2-phosphate ester + H2O + diphosphate
show the reaction diagram
-
glycerol 2-phosphate + H2O = glycerol + phosphate
show the reaction diagram
-
glycerol 2-phosphate + H2O = glycerol + phosphate
show the reaction diagram
-
beta-glycerophosphate + H2O = glycerol + phosphate
show the reaction diagram
-
beta-glycerophosphate + H2O = glycerol + phosphate
show the reaction diagram
-
beta-glycerol phosphate + H2O = glycerol + phosphate
show the reaction diagram
-
beta-glycerophosphate + H2O = glycerol + phosphate
show the reaction diagram
-
glycerol 2-phosphate + H2O = glycerol + phosphate
show the reaction diagram
-
beta-glycerophosphate + H2O = ?
show the reaction diagram
-

Activator in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
activation
-

Inhibitor in Enzyme-catalyzed Reactions (10 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
competitive
-
0.3 mM, 40% inhibition
-

3D Structure of Enzyme-Ligand-Complex (PDB) (16 results)

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (6 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
10.18
-
pH 7.4, 37°C
0.18
-
in Tris-HCl 50 mM at pH 7.5, at 22°C
102
-
-
4
-
-

KM Value (37 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
100
-
-
0.0062
-
-
2.01
-
in Tris-HCl 50 mM at pH 7.5, at 22°C

Ki Value (3 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.339
-
-
9.6
-
pH 7.5, 20°C, versus 3-phospho-D-glycerate

IC50 Value (1 result)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE
18
-
-

References & Links

Links to other databases for glycerol 2-phosphate

ChEBI
PubChem
ChEBI
PubChem