Ligand Mevinolin
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Basic Ligand Information
Molecular Structure

C24H36O5
Mevinolin
PCZOHLXUXFIOCF-UHFFFAOYSA-N
Roles as Enzyme Ligand
Inhibitor in Enzyme-catalyzed Reactions (2 results)
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competitive with 3-hydroxy-3-methylglutaryl-CoA
-
Enzyme Kinetic Parameters
Ki Value (1 result)
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0.000005
-
pH 5.5, 50°C
255
IC50 Value (1 result)
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0.18
-
50°C, pH not specified in the publication
References & Links
Literature References (2)
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Expression and characterization of the HMG-CoA reductase of the thermophilic archaeon Sulfolobus solfataricus
1999
Kim, D.Y.; Bochar, D.A.; Stauffacher, C.V.; Rodwell, V.W.
Protein Expr. Purif.
17
435-442
Dual coenzyme specificity of Archaeoglobus fulgidus HMG-CoA reductase
2000
Kim, D.Y.; Stauffacher, C.V.; Rodwell, V.W.
Protein Sci.
9
1226-1234
Links to other databases for Mevinolin