Ligand 7,8-dihydro-L-monapterin

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Basic Ligand Information

Molecular Structure
Picture of 7,8-dihydro-L-monapterin (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C9H13N5O4
7,8-dihydro-L-monapterin
YQIFAMYNGGOTFB-NJGYIYPDSA-N
Synonyms:
2-amino-4-hydroxy-6-(L-threo-1,2,3-trihydroxypropyl)-7,8-dihydropteridine, 7,8-dihydromonapterin, L-threo-7,8-dihydroneopterin, L-threo-dihydroneopterin, quinonoid dihydro-L-threo-neopterin, quinonoid L-threo-dihydroneopterin


Show all pahtways known for Show all BRENDA pathways known for 7,8-dihydro-L-monapterin

Roles as Enzyme Ligand

In Vivo Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
6-hydroxymethyl-7,8-dihydropterin + glycolaldehyde = 7,8-dihydroneopterin + 7,8-dihydromonapterin
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Substrate in Enzyme-catalyzed Reactions (10 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
L-threo-dihydroneopterin + NADP+ = ?
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L-threo-7,8-dihydroneopterin + NADPH = ?
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quinonoid dihydro-L-threo-neopterin + NAD(P)H = tetrahydro-L-threo-neopterin + NAD(P)+
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7,8-dihydromonapterin + NADPH + H+ = 5,6,7,8-tetrahydromonapterin + NADP+
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7,8-dihydromonapterin = 7,8-dihydroneopterin
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7,8-dihydromonapterin = 7,8-dihydroneopterin
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
6-hydroxymethyl-7,8-dihydropterin + glycolaldehyde = 7,8-dihydroneopterin + 7,8-dihydromonapterin
show the reaction diagram
7,8-dihydroneopterin = 7,8-dihydromonapterin
show the reaction diagram
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7,8-dihydroneopterin = 7,8-dihydromonapterin
show the reaction diagram
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3D Structure of Enzyme-Ligand-Complex (PDB) (1 result)

EC NUMBER
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (9 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE

KM Value (16 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
1.45
-
-
0.147
-
pH 6.0, 22°C
0.066
-
pH 6.2, 37°C, recombinant enzyme
0.066
-
pH 8.0, 55°C

References & Links

Links to other databases for 7,8-dihydro-L-monapterin

ChEBI
PubChem
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PubChem