Ligand 5-hydroxylysine

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Basic Ligand Information

Molecular Structure
Picture of 5-hydroxylysine (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C6H14N2O3
5-hydroxylysine
YSMODUONRAFBET-WHFBIAKZSA-N
Synonyms:
5-hydroxy-L-lysine, 5-hydroxy-lysine, allohydroxy-L-lysine, delta-hydroxylysine, DL-allo-5-Hydroxylysine, DL/DL-Allo-delta-hydroxylysine, hydroxy-L-lysine, hydroxylysine
Pathway Source
Pathways

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
GTP + 5-hydroxy-L-lysine = GDP + O-phosphohydroxy-L-lysine
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (9 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
5-hydroxylysine + O2 = ?
show the reaction diagram
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DL/DL-Allo-delta-hydroxylysine + NADPH + O2 = ?
show the reaction diagram
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5-hydroxylysine + NADP+ = alpha-amino-delta-hydroxyadipate-semialdehyde + NADPH
show the reaction diagram
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delta-Hydroxylysine = 1,5-Diamino-2-hydroxypentane + CO2
show the reaction diagram
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5-hydroxylysine = ?
show the reaction diagram
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ATP + 5-hydroxylysine + beta-Ala = AMP + phosphate + beta-Ala-5-hydroxylysine
show the reaction diagram
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Inhibitor in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
competitive with respect to alpha-aminoadipate, non-competitive with respect to both ATP and NADPH
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weak
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3D Structure of Enzyme-Ligand-Complex (PDB) (1 result)

EC NUMBER
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

KM Value (6 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
7
-
-

Ki Value (1 result)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
1.65
-
-

References & Links

Links to other databases for 5-hydroxylysine

ChEBI
PubChem
ChEBI
PubChem