Ligand methanethiol

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Basic Ligand Information

Molecular Structure
Picture of methanethiol (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
CH4S
methanethiol
LSDPWZHWYPCBBB-UHFFFAOYSA-N
Synonyms:
CH3SH, H-S-CH3, methanthiol, methyl-mercaptan, methyl-mercaptane, methylmercaptan, methyl mercaptan, methyl mercaptane, methylthiol, thiomethanol


Show all pahtways known for Show all BRENDA pathways known for methanethiol

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
LITERATURE
REACTION DIAGRAM
PROVEN IN VIVO REACTION
ENZYME 3D STRUCTURE
show the reaction diagram
methanethiol + O2 + H2O = formaldehyde + H2S + H2O2
-
show the reaction diagram
S-adenosyl-L-methionine + methanethiol = S-adenosyl-L-homocysteine + dimethyl sulfide
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show the reaction diagram
O-acetyl-L-homoserine + methanethiol = L-methionine + acetate
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In Vivo Product in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
LITERATURE
REACTION DIAGRAM
PROVEN IN VIVO REACTION
ENZYME 3D STRUCTURE
-
show the reaction diagram
dimethylsulfide + coenzyme M = methyl-CoM + methanethiol
-
-
show the reaction diagram
3-(methylthio)acryloyl-CoA + 2 H2O = acetaldehyde + methanethiol + CoA + CO2
-
-
show the reaction diagram
L-methionine + H2O = methanethiol + NH3 + 2-oxobutanoate
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Substrate in Enzyme-catalyzed Reactions (22 results)

EC NUMBER
LITERATURE
REACTION DIAGRAM
REACTION
ENZYME 3D STRUCTURE
show the reaction diagram
methylmercaptan + NADPH + H+ + O2 = ? + NADP+ + H2O
-
show the reaction diagram
methanethiol + O2 + H2O = formaldehyde + H2S + H2O2
-
show the reaction diagram
S-adenosyl-L-methionine + methanethiol = S-adenosyl-L-homocysteine + dimethyl sulfide
-
show the reaction diagram
methylmercaptan + S-adenosyl-L-methionine = dimethylsulfide + S-adenosyl-L-homocysteine
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show the reaction diagram
L-vinylglycine + methanethiol = methionine
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show the reaction diagram
methanethiol + acetyl-CoA = methanethioacetate + coenzyme A
-
show the reaction diagram
L-Cys + methanethiol = ?
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show the reaction diagram
3-chloro-D-alanine + methyl-mercaptane = S-methyl-D-cysteine
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show the reaction diagram
3-chloro-L-alanine + methylmercaptan = S-methyl-L-cysteine + Cl-
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Product in Enzyme-catalyzed Reactions (46 results)

EC NUMBER
LITERATURE
REACTION DIAGRAM
REACTION
ENZYME 3D STRUCTURE
-
show the reaction diagram
dimethylsulfide + coenzyme M = methyl-CoM + methanethiol
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-
show the reaction diagram
S-methyl hydroxy(phenyl)ethanethioate + H2O = methanethiol + hydroxy(phenyl)acetic acid
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-
show the reaction diagram
methylthio-beta-D-galactoside + H2O = galactose + methanethiol
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-
show the reaction diagram
gamma-thiomethyl glutamate + H2O = Glu + thiomethanol
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-
show the reaction diagram
ametryn + H2O = 4-(ethylamino)-2-hydroxy-6-(isopropylamino)-1,3,5-triazine + H-S-CH3
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-
show the reaction diagram
3-(methylthio)acryloyl-CoA + 2 H2O = acetaldehyde + methanethiol + CoA + CO2
-
-
show the reaction diagram
S-methyl-D-cysteine + H2O = methanethiol + pyruvate + NH3
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show the reaction diagram
S-methyl-L-cysteine + H2O = methanethiol + NH3 + 2-oxopropanoate
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Inhibitor in Enzyme-catalyzed Reactions (3 results)

COMMENTARY
EC NUMBER
LITERATURE
ENZYME 3D STRUCTURE
above 0.014 mM
-

3D Structure of Enzyme-Ligand-Complex (PDB) (49 results)

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (1 result)

COMMENTARY
EC NUMBER
LITERATURE
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
pH 7.5, 25°C
96.65
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KM Value (7 results)

COMMENTARY
EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
LITERATURE
pH 7.3, 30°C, gamma-replacement reaction
100
-
pH 7.5, 25°C
0.4
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Ki Value (2 results)

COMMENTARY
EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
LITERATURE

References & Links

Links to other databases for methanethiol

ChEBI
PubChem
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PubChem