Ligand D-glyceraldehyde 3-phosphate

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Basic Ligand Information

Molecular Structure
Picture of D-glyceraldehyde 3-phosphate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C3H7O6P
D-glyceraldehyde 3-phosphate
LXJXRIRHZLFYRP-VKHMYHEASA-N
Synonyms:
(2R)-2-hydroxy-3-oxopropyl dihydrogen phosphate, D-3-Glyceraldehyde phosphate, D-Glyceraldehyde-3-phosphate, D-glyceraldehyde-phosphate
Pathway Source
Pathways
MetaCyc
1,3-propanediol biosynthesis (engineered), 2-deoxy-alpha-D-ribose 1-phosphate degradation, 2-deoxy-D-ribose degradation I, 3,6-anhydro-alpha-L-galactopyranose degradation, 3-dehydroquinate biosynthesis II (archaea) more


Show all pahtways known for Show all BRENDA pathways known for D-glyceraldehyde 3-phosphate

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (60 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
D-glyceraldehyde 3-phosphate + phosphate + NADP+ = 3-phospho-D-glyceroyl phosphate + NADPH + H+
show the reaction diagram
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sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate
show the reaction diagram
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pyruvate + D-glyceraldehyde 3-phosphate = 1-deoxy-D-xylulose 5-phosphate + CO2
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pyruvate + D-glyceraldehyde 3-phosphate = 2-dehydro-3-deoxy-6-phospho-D-gluconate
show the reaction diagram
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dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate = ?
show the reaction diagram
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pyruvate + D-glyceraldehyde 3-phosphate = 2-dehydro-3-deoxy-6-phospho-D-galactonate
show the reaction diagram
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D-Glyceraldehyde 3-phosphate + acetaldehyde = ?
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D-glyceraldehyde 3-phosphate + glycerone phosphate = (5-formylfuran-3-yl)methyl phosphate + phosphate + 2 H2O
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D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + L-glutamine = pyridoxal 5'-phosphate + L-glutamate + 3 H2O + phosphate
show the reaction diagram

In Vivo Product in Enzyme-catalyzed Reactions (63 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
sn-glycerol 3-phosphate + NADP+ = D-glyceraldehyde 3-phosphate + NADPH + H+
show the reaction diagram
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3-phospho-D-glyceroyl phosphate + NADPH + H+ = D-glyceraldehyde 3-phosphate + phosphate + NADP+
show the reaction diagram
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methylglyoxal + D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + 1-deoxy-D-threo-hexo-2,5-diulose 6-phosphate
show the reaction diagram
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D-erythrose 4-phosphate + D-fructose 6-phosphate = sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate
show the reaction diagram
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2-dehydro-3-deoxy-6-phospho-D-gluconate = pyruvate + D-glyceraldehyde 3-phosphate
show the reaction diagram
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2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde
show the reaction diagram
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(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate = indole + D-glyceraldehyde 3-phosphate
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D-Xylulose 5-phosphate + phosphate = Acetyl phosphate + D-glyceraldehyde 3-phosphate + H2O
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Substrate in Enzyme-catalyzed Reactions (194 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
D-glyceraldehyde 3-phosphate + NADPH = L-alpha-glycerol 3-phosphate + NADP+
show the reaction diagram
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D-glyceraldehyde 3-phosphate + NAD+ + H2O = D-glycerate 3-phosphate + NADH + H+
show the reaction diagram
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D-glyceraldehyde 3-phosphate + NADP+ + H2O = D-glycerate 3-phosphate + NADPH + H+
show the reaction diagram
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D-glyceraldehyde-3-phosphate + H2O + methyl viologen = 3-phospho-D-glycerate + reduced methyl viologen
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D-glyceraldehyde 3-phosphate + H2O = D-glyceraldehyde + phosphate
show the reaction diagram
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dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate = ?
show the reaction diagram
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D-Glyceraldehyde 3-phosphate = Glycerone phosphate
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (102 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
3-phospho-D-glyceroyl phosphate + NADPH + H+ = D-glyceraldehyde 3-phosphate + phosphate + NADP+
show the reaction diagram
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methylglyoxal + D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + 1-deoxy-D-threo-hexo-2,5-diulose 6-phosphate
show the reaction diagram
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2-dehydro-3-deoxy-D-gluconate 6-phosphate = pyruvate + D-glyceraldehyde 3-phosphate
show the reaction diagram
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Inhibitor in Enzyme-catalyzed Reactions (23 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
recombinant GAPOR is posttranscriptionally regulated as it exhibits pronounced and irreversible substrate inhibition. Inhibition is independent of benzyl viologen
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substrate inhibition
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3D Structure of Enzyme-Ligand-Complex (PDB) (33 results)

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (220 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
0.83
-
pH 8, 80°C
0.00017
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pH 8.5, 37°C

KM Value (340 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
1
-
pH 6.6, 70°C
6.12
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pH 8, 80°C
38
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at pH 7.0 and 42°C
1.1
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cosubstrate L-Trp, i.e. reverse reaction

Ki Value (6 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.1
-
pH 6.6, 70°C

References & Links